Biomaterial Database

The kinetics of homosynaptic short-term depression in cell RPa3 of Helix pomatia depends upon the level of activity prior to depression. 1992

G R Christoffersen

Zoophysiological Laboratory B, August Krogh Institute, University of Copenhagen, Denmark.

1. Following synaptic rest periods of 2 min, recovery from EPSP depression was dominated by a monoexponential phase completed within 2 min. After rest periods of 6 min, a two-phased recovery occurred: a transient phase followed by a slow phase lasting 10 min. 2. The shift of recovery kinetics was associated with a change of the time course of depression: following rest periods of 2, 6 and 12 min, EPSP trains of 1/10 Hz gave three different depressions. 3. The change of recovery inverted a logarithmic proportionality between frequency of EPSPs and degree of depression to an inverse relation.

UI	MeSH Term	Description	Entries
D007700	Kinetics	The rate dynamics in chemical or physical systems.
D005073	Evoked Potentials, Somatosensory	The electric response evoked in the CEREBRAL CORTEX by stimulation along AFFERENT PATHWAYS from PERIPHERAL NERVES to CEREBRUM.	Somatosensory Evoked Potentials,Evoked Potential, Somatosensory,Somatosensory Evoked Potential
D006372	Helix, Snails	A genus of chiefly Eurasian and African land snails including the principal edible snails as well as several pests of cultivated plants.	Helix (Snails),Snails Helix
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D013569	Synapses	Specialized junctions at which a neuron communicates with a target cell. At classical synapses, a neuron's presynaptic terminal releases a chemical transmitter stored in synaptic vesicles which diffuses across a narrow synaptic cleft and activates receptors on the postsynaptic membrane of the target cell. The target may be a dendrite, cell body, or axon of another neuron, or a specialized region of a muscle or secretory cell. Neurons may also communicate via direct electrical coupling with ELECTRICAL SYNAPSES. Several other non-synaptic chemical or electric signal transmitting processes occur via extracellular mediated interactions.	Synapse