[Veratrum alkaloids. X. Relation between structure & biological action of veratrum alkaloid esters].
1957
Z J VEJDELEK, and
TRCKA
UI
MeSH Term
Description
Entries
D004952
Esters
Compounds derived from organic or inorganic acids in which at least one hydroxyl group is replaced by an –O-alkyl or another organic group. They can be represented by the structure formula RCOOR’ and are usually formed by the reaction between an acid and an alcohol with elimination of water.
Ester
D014703
Veratrum
A plant genus of the family Melanthiaceae with roots that contain VERATRUM ALKALOIDS used as emetics, parasiticides, antihypertensives. The common name "black hellebore" is used for both Veratrum nigrum and HELLEBORUS NIGER.
Alkaloids with powerful hypotensive effects isolated from American or European Hellebore (Veratrum viride Ait. Liliaceae and Veratrum album L. Liliaceae). They increase cholinergic and decrease adrenergic tone with appropriate side effects and at higher doses depress respiration and produce cardiac arrhythmias; only the ester alkaloids have been used as hypotensive agents in specific instances. They have been generally replaced by drugs with fewer adverse effects.