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The generation of mouse cytolytic T lymphocytes (CTL) in primary or secondary mixed leukocyte cultures (MLC) is greatly enhanced by the addition of 2-mercaptoethanol (2-ME) to the culture medium. This enhancement can be equally demonstrated with either reduced or oxidized 2-ME. Addition of 2-ME to MLC as late as 3 days after the initiation of the culture results in a peak CTL response which is nearly as high as the one in cultures containing 2-ME throughout the 4 day-incubation period. Quantitative analysis of the CTL response in MLC supplemented with 2-ME on day 3 shows a 50-fold increase in lytic activity within 24 h, suggesting that cell differentiation, in addition to proliferation may be affected by this agent.
H D Engers, and
H R MacDonald, and
J C Cerottini, and
K T Brunner
January 1980,
Scandinavian journal of immunology,
H D Engers, and
H R MacDonald, and
J C Cerottini, and
K T Brunner
April 1974,
The Journal of experimental medicine,
H D Engers, and
H R MacDonald, and
J C Cerottini, and
K T Brunner
June 1977,
European journal of immunology,
H D Engers, and
H R MacDonald, and
J C Cerottini, and
K T Brunner
April 1984,
Pathologie-biologie,
H D Engers, and
H R MacDonald, and
J C Cerottini, and
K T Brunner
July 1988,
Journal of immunology (Baltimore, Md. : 1950),
H D Engers, and
H R MacDonald, and
J C Cerottini, and
K T Brunner
February 1976,
Transplantation,
H D Engers, and
H R MacDonald, and
J C Cerottini, and
K T Brunner
October 1976,
Acta pathologica et microbiologica Scandinavica. Section C, Immunology,
H D Engers, and
H R MacDonald, and
J C Cerottini, and
K T Brunner
September 1981,
Journal of immunology (Baltimore, Md. : 1950),
H D Engers, and
H R MacDonald, and
J C Cerottini, and
K T Brunner
December 1974,
The Journal of experimental medicine,
H D Engers, and
H R MacDonald, and
J C Cerottini, and
K T Brunner
May 1985,
Cellular immunology,
