-transparent.png){kind=logo}
High concentrations of serum lipoprotein(a) (Lp(a)) are associated with an increased risk of atherosclerotic vascular disease in the nontransplanted population. However, its relation with accelerated coronary artery disease (CAD) in cardiac transplant recipients has not been reported. We measured serum Lp(a) in 130 cardiac transplant recipients undergoing routine follow-up, which included annual coronary angiography. The median Lp(a) concentration in 33 patients with CAD was 71 mg/dl, which was significantly higher than the corresponding value of 22 mg/dL in the 97 patients without CAD (p = 0.0006). Multivariant analysis showed the serum Lp(a) value to be a higher significant risk factor for CAD irrespective of the other factors included in the regression analysis. Thus a high concentration of serum Lp(a) is an important, independent risk factor for the development of accelerated CAD in transplant recipients.
M Barbir, and
S Kushwaha, and
B Hunt, and
A Macken, and
G R Thompson, and
A Mitchell, and
D Robinson, and
M Yacoub
March 1995,
Coronary artery disease,
M Barbir, and
S Kushwaha, and
B Hunt, and
A Macken, and
G R Thompson, and
A Mitchell, and
D Robinson, and
M Yacoub
February 1996,
The Medical journal of Australia,
M Barbir, and
S Kushwaha, and
B Hunt, and
A Macken, and
G R Thompson, and
A Mitchell, and
D Robinson, and
M Yacoub
August 1995,
The Medical journal of Australia,
M Barbir, and
S Kushwaha, and
B Hunt, and
A Macken, and
G R Thompson, and
A Mitchell, and
D Robinson, and
M Yacoub
January 1990,
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery,
M Barbir, and
S Kushwaha, and
B Hunt, and
A Macken, and
G R Thompson, and
A Mitchell, and
D Robinson, and
M Yacoub
August 2001,
Clinical transplantation,
M Barbir, and
S Kushwaha, and
B Hunt, and
A Macken, and
G R Thompson, and
A Mitchell, and
D Robinson, and
M Yacoub
January 1987,
Transplantation reviews (Orlando, Fla.),
M Barbir, and
S Kushwaha, and
B Hunt, and
A Macken, and
G R Thompson, and
A Mitchell, and
D Robinson, and
M Yacoub
November 1988,
The American journal of cardiology,
M Barbir, and
S Kushwaha, and
B Hunt, and
A Macken, and
G R Thompson, and
A Mitchell, and
D Robinson, and
M Yacoub
October 1995,
Transplantation proceedings,
M Barbir, and
S Kushwaha, and
B Hunt, and
A Macken, and
G R Thompson, and
A Mitchell, and
D Robinson, and
M Yacoub
July 1990,
Seminars in thoracic and cardiovascular surgery,
M Barbir, and
S Kushwaha, and
B Hunt, and
A Macken, and
G R Thompson, and
A Mitchell, and
D Robinson, and
M Yacoub
November 1997,
European heart journal,
