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Adrenal corticoid activities of 9 alpha-fluoro-11 beta, 16 alpha, 17 alpha, 21-tetrahydroxy-1, 4-pregnadiene-3, 20-dione.
1959
J W PERRINE, and L BORTLE, and E HEYDER, and R PARTRIDGE, and E K ROSS, and I RINGLER
Associated MeSH Terms
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UI
MeSH Term
Description
Entries
D011245
Pregnadienes
Pregnane derivatives containing two double bonds anywhere within the ring structures.
D005438
Fludrocortisone
A synthetic mineralocorticoid with anti-inflammatory activity.
9-Fluorocortisol,9 alpha Fludrohydrocortisone,9 alpha-Fluoro-17-Hydroxycorticosterone,9 alpha-Fluorohydrocortisone,9-Fluoro-17-Hydroxycortisone,9-Fluorohydrocortisone,Astonin,Astonin Merck,Astonin-H,FCOL,9 Fluoro 17 Hydroxycortisone,9 Fluorocortisol,9 Fluorohydrocortisone,9 alpha Fluoro 17 Hydroxycorticosterone,9 alpha Fluorohydrocortisone,Astonin H,Merck, Astonin
D000305
Adrenal Cortex Hormones
HORMONES produced by the ADRENAL CORTEX, including both steroid and peptide hormones. The major hormones produced are HYDROCORTISONE and ALDOSTERONE.
Adrenal Cortex Hormone,Corticoid,Corticoids,Corticosteroid,Corticosteroids,Cortex Hormone, Adrenal,Hormone, Adrenal Cortex,Hormones, Adrenal Cortex
Related Publications
J W PERRINE, and L BORTLE, and E HEYDER, and R PARTRIDGE, and E K ROSS, and I RINGLER
[A new synthetic cortisonic drug, dexamethasone (9 alpha-fluoro-16 alpha-methyl-1, 4-pregnadiene-11 beta, 17 alpha, 21-triol-3, 20-dione), in treatment of rheumatoid arthritis].
November 1958, Minerva medica,
J W PERRINE, and L BORTLE, and E HEYDER, and R PARTRIDGE, and E K ROSS, and I RINGLER
Esters of 9-alpha-fluoro-16-alpha, 17-alpha-isopropylidenedioxy-5-alpha-pregnane-11-beta, 21-diol-3, 20-dione.
September 1965, Steroids,
J W PERRINE, and L BORTLE, and E HEYDER, and R PARTRIDGE, and E K ROSS, and I RINGLER
New steroidal anti-inflammatory antedrugs: methyl 3,20-dioxo-9 alpha-fluoro-11 beta,17 alpha,21-trihydroxy-1,4-pregnadiene-16 alpha-carboxylate and methyl 21-acetyloxy-3,20-dioxo-11 beta, 17 alpha-dihydroxy-9 alpha-fluoro-1,4-pregnadiene-16 alpha-carboxylate.
June 1997, Steroids,
J W PERRINE, and L BORTLE, and E HEYDER, and R PARTRIDGE, and E K ROSS, and I RINGLER
[Studies on the production of 16 beta-methyl-11 alpha,17 alpha,21-trihydroxy-1,4-pregnadiene-3,20-dione from 16 beta-methyl-17 alpha,21-dihydroxy-1,4-pregnadiene-3,20-dione-21-acetate by Absidia].
July 2000, Sheng wu gong cheng xue bao = Chinese journal of biotechnology,
J W PERRINE, and L BORTLE, and E HEYDER, and R PARTRIDGE, and E K ROSS, and I RINGLER
[Preparation of 6-alpha-fluoro-11-beta, 21-dihydroxy-16-alpha-methyl-1,4-pregnadiene-3, 20-dione (fluocortolone) via substrate-structure-directed specific 11-beta-hydroxylation by Curvularia lunata].
January 1969, Justus Liebigs Annalen der Chemie,
J W PERRINE, and L BORTLE, and E HEYDER, and R PARTRIDGE, and E K ROSS, and I RINGLER
Biological activity of 9 alpha-fluoro-11 beta-hydroxy-delta 4-androstene-3, 17-dione.
November 1958, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.),
J W PERRINE, and L BORTLE, and E HEYDER, and R PARTRIDGE, and E K ROSS, and I RINGLER
Urinary excretion by man of 11 beta, 17 alpha, 20 alpha, 21-tetrahydroxy-4-pregnen-3-one and the 20 beta epimer.
December 1958, The Journal of clinical endocrinology and metabolism,
J W PERRINE, and L BORTLE, and E HEYDER, and R PARTRIDGE, and E K ROSS, and I RINGLER
Studies on topical antiinflammatory agents. III. Synthesis of 17 alpha-acyloxy-9 alpha-fluoro-11 beta-hydroxy-16 beta-methyl-1,4-pregnadiene-3,20-dione 21-thio derivatives and related compounds.
December 1989, Chemical & pharmaceutical bulletin,
J W PERRINE, and L BORTLE, and E HEYDER, and R PARTRIDGE, and E K ROSS, and I RINGLER
New steroidal antiinflammatory antedrugs: Methyl 3,20-dioxo-9 alpha-fluoro-11 beta,17 alpha,21-trihydroxy-1,4-pregnadiene-16 alpha-carboxylate and its 21-O-acyl derivatives.
March 2002, Steroids,
J W PERRINE, and L BORTLE, and E HEYDER, and R PARTRIDGE, and E K ROSS, and I RINGLER
The synthesis of 6-alpha,16-beta-dimethyl-9-alpha,11-beta-dichloro-1,4-pregnadiene-17-alpha,21-diol-3,20-diones.
March 1966, Steroids,
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