[Congenital hypothyroidism with goiter caused by defect in conversion of inorganic iodine to organic iodine].
1959
J ROCHE, and
R JOSEPH, and
R MICHEL, and
M TUBIANA, and
J C JOB, and
M RIBIERRE
UI
MeSH Term
Description
Entries
D007454
Iodides
Inorganic binary compounds of iodine or the I- ion.
Iodide
D007455
Iodine
A nonmetallic element of the halogen group that is represented by the atomic symbol I, atomic number 53, and atomic weight of 126.90. It is a nutritionally essential element, especially important in thyroid hormone synthesis. In solution, it has anti-infective properties and is used topically.
Iodine-127,Iodine 127
D003409
Congenital Hypothyroidism
A condition in infancy or early childhood due to an in-utero deficiency of THYROID HORMONES that can be caused by genetic or environmental factors, such as thyroid dysgenesis or HYPOTHYROIDISM in infants of mothers treated with THIOURACIL during pregnancy. Endemic cretinism is the result of iodine deficiency. Clinical symptoms include severe MENTAL RETARDATION, impaired skeletal development, short stature, and MYXEDEMA.
Enlargement of the THYROID GLAND that may increase from about 20 grams to hundreds of grams in human adults. Goiter is observed in individuals with normal thyroid function (euthyroidism), thyroid deficiency (HYPOTHYROIDISM), or hormone overproduction (HYPERTHYROIDISM). Goiter may be congenital or acquired, sporadic or endemic (GOITER, ENDEMIC).
Goiters
Related Publications
J ROCHE, and
R JOSEPH, and
R MICHEL, and
M TUBIANA, and
J C JOB, and
M RIBIERRE