-transparent.png){kind=logo}
Quadriceps muscle biopsies from 24 patients with amyotrophic lateral sclerosis (ALS) and 15 age-matched controls were prepared for histochemistry and analyzed morphometrically. Pathological features for denervation and reinnervation were observed in most ALS patients, although considerable variation between patients was noted. Myopathic changes were also seen in one-third of the cases. The morphometric data were not only related to the duration and mean diameter of type I fiber, but also to the duration and hypertrophy factor of type II fiber, suggesting that the progression and severity of ALS depends on the preservation of both fibers.
Related Publications
Y Iwasaki, and
H Sugimoto, and
K Ikeda, and
K Takamiya, and
T Shiojima, and
M Kinoshita
March 1988,
Muscle & nerve,
Y Iwasaki, and
H Sugimoto, and
K Ikeda, and
K Takamiya, and
T Shiojima, and
M Kinoshita
November 2023,
Brain : a journal of neurology,
Y Iwasaki, and
H Sugimoto, and
K Ikeda, and
K Takamiya, and
T Shiojima, and
M Kinoshita
March 1978,
The American review of respiratory disease,
Y Iwasaki, and
H Sugimoto, and
K Ikeda, and
K Takamiya, and
T Shiojima, and
M Kinoshita
March 2008,
Ultrasound in medicine & biology,
Y Iwasaki, and
H Sugimoto, and
K Ikeda, and
K Takamiya, and
T Shiojima, and
M Kinoshita
February 1978,
Chest,
Y Iwasaki, and
H Sugimoto, and
K Ikeda, and
K Takamiya, and
T Shiojima, and
M Kinoshita
September 1998,
American journal of respiratory and critical care medicine,
Y Iwasaki, and
H Sugimoto, and
K Ikeda, and
K Takamiya, and
T Shiojima, and
M Kinoshita
October 2015,
Current osteoporosis reports,
Y Iwasaki, and
H Sugimoto, and
K Ikeda, and
K Takamiya, and
T Shiojima, and
M Kinoshita
April 1971,
Mayo Clinic proceedings,
Y Iwasaki, and
H Sugimoto, and
K Ikeda, and
K Takamiya, and
T Shiojima, and
M Kinoshita
October 2014,
Annals of clinical and translational neurology,
Y Iwasaki, and
H Sugimoto, and
K Ikeda, and
K Takamiya, and
T Shiojima, and
M Kinoshita
May 1966,
Neurology,
