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A mutant of Neurospora crassa with an altered repressible acid phosphatase has been isolated. The enzyme is much more thermolabile than that of wild type, and has an increased Michaelis constant. Tests of allelic interactions (in partial diploids) and in vitro mixing experiments were consistent with the mutation being in the structural gene for the enzyme. This gene, pho-3, was found to be located in the right arm of Linkage Group IV (LGIV). Thus, pho-3 and the structural gene for repressible alkaline phosphatase, pho-2 (LG V), map in separate linkage groups and cannot be part of the same operon. Neither of these structural genes is linked to the known regulatory genes, nuc-1 (LG I), nuc-2 (LG II), and preg (LG II).
R E Nelson, and
J F Lehman, and
R L Metzenberg
October 1976,
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R E Nelson, and
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R L Metzenberg
April 1967,
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R E Nelson, and
J F Lehman, and
R L Metzenberg
October 1974,
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R E Nelson, and
J F Lehman, and
R L Metzenberg
January 1973,
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R E Nelson, and
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R E Nelson, and
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R L Metzenberg
April 1995,
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R E Nelson, and
J F Lehman, and
R L Metzenberg
March 1971,
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R E Nelson, and
J F Lehman, and
R L Metzenberg
October 1969,
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R E Nelson, and
J F Lehman, and
R L Metzenberg
March 1980,
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R E Nelson, and
J F Lehman, and
R L Metzenberg
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