Studies on the mechanism of properdin--zymosan reaction. The role of polysaccharide structure in combination with properdin.
1961
G CSEH, and
I SZABO
UI
MeSH Term
Description
Entries
D011134
Polysaccharides
Long chain polymeric CARBOHYDRATES composed of MONOSACCHARIDES linked by glycosidic bonds.
Glycan,Glycans,Polysaccharide
D011414
Properdin
A 53-kDa protein that is a positive regulator of the alternate pathway of complement activation (COMPLEMENT ACTIVATION PATHWAY, ALTERNATIVE). It stabilizes the ALTERNATIVE PATHWAY C3 CONVERTASE (C3bBb) and protects it from rapid inactivation, thus facilitating the cascade of COMPLEMENT ACTIVATION and the formation of MEMBRANE ATTACK COMPLEX. Individuals with mutation in the PFC gene exhibit properdin deficiency and have a high susceptibility to infections.
Complement Factor P,Factor P, Complement
D004040
Dietary Carbohydrates
Carbohydrates present in food comprising digestible sugars and starches and indigestible cellulose and other dietary fibers. The former are the major source of energy. The sugars are in beet and cane sugar, fruits, honey, sweet corn, corn syrup, milk and milk products, etc.; the starches are in cereal grains, legumes (FABACEAE), tubers, etc. (From Claudio & Lagua, Nutrition and Diet Therapy Dictionary, 3d ed, p32, p277)