-transparent.png){kind=logo}
CD5+ B cells and other lymphocyte subsets were analyzed by flow cytometry in patients with primary Sjögren's syndrome (pSS), in healthy subjects (HS) and in patients with various control diseases. When compared with HS, patients with pSS were found to have similar levels of CD5+ B cells and decreased levels of CD8+ T cells (P = 0.0003). When compared with patients with various other diseases, however, the number of CD5+ B cells in pSS was more than twice as high (P = 0.0002), whereas no difference was found between numbers of CD8+ T cells. When the number of CD5+ B cells was expressed as a percentage of total B cells, the results obtained were similar to those with absolute numbers. Determination of lymphocyte subsets may be used as a diagnostic aid for Sjögren's syndrome in selected patients with suspected immunological diseases of unknown type.
J P van de Merwe, and
M W van den Beemd, and
H Hooijkaas
January 1990,
Allergologia et immunopathologia,
J P van de Merwe, and
M W van den Beemd, and
H Hooijkaas
April 1988,
Journal of autoimmunity,
J P van de Merwe, and
M W van den Beemd, and
H Hooijkaas
May 1993,
Clinical and experimental immunology,
J P van de Merwe, and
M W van den Beemd, and
H Hooijkaas
January 2020,
Clinical and experimental rheumatology,
J P van de Merwe, and
M W van den Beemd, and
H Hooijkaas
January 1990,
Clinical and experimental rheumatology,
J P van de Merwe, and
M W van den Beemd, and
H Hooijkaas
August 1989,
Clinical and experimental immunology,
J P van de Merwe, and
M W van den Beemd, and
H Hooijkaas
December 2008,
La Revue de medecine interne,
J P van de Merwe, and
M W van den Beemd, and
H Hooijkaas
July 2015,
Infection and immunity,
J P van de Merwe, and
M W van den Beemd, and
H Hooijkaas
May 1988,
Arthritis and rheumatism,
J P van de Merwe, and
M W van den Beemd, and
H Hooijkaas
July 1991,
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.),
