Congeners of pempidine with high ganglion-blocking activity. 1959

L BRETHERICK, and G E LEE, and E LUNT, and W R WRAGG, and N D EDGE

UI MeSH Term Description Entries
D010393 Pempidine A nicotinic antagonist most commonly used as an experimental tool. It has been used as a ganglionic blocker in the treatment of hypertension but has largely been supplanted for that purpose by more specific drugs.
D010880 Piperidines A family of hexahydropyridines.
D005724 Ganglia Clusters of multipolar neurons surrounded by a capsule of loosely organized CONNECTIVE TISSUE located outside the CENTRAL NERVOUS SYSTEM.

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