-transparent.png){kind=logo}
Chrysotile asbestos stimulates T lymphocyte subsets. Cell surface CD4 or CD45RA expression in peripheral blood mononuclear cells (PBMC) was downregulated after incubation with chrysotile asbestos in vitro temporarily. The percentage of CD4+CD45RA+ cells and mean fluorescence intensity in CD4 or CD45RA decreased after incubation with asbestos and returned to the original level after 24 h of incubation, which suggests that chrysotile asbestos activates CD4+CD45RA+ cells. No change was observed in CD29 expression. An increased percentage of IL-2R positive cells and an elevated intracellular Ca++ level were also indicative of the activation of PBMC by chrysotile asbestos.
Related Publications
K Kinugawa, and
A Ueki, and
M Yamaguchi, and
Y Watanabe, and
Y Kawakami, and
F Hyodoh, and
H Tsushima
February 1993,
Research in immunology,
K Kinugawa, and
A Ueki, and
M Yamaguchi, and
Y Watanabe, and
Y Kawakami, and
F Hyodoh, and
H Tsushima
February 2022,
International journal of molecular sciences,
K Kinugawa, and
A Ueki, and
M Yamaguchi, and
Y Watanabe, and
Y Kawakami, and
F Hyodoh, and
H Tsushima
May 1992,
Immunology,
K Kinugawa, and
A Ueki, and
M Yamaguchi, and
Y Watanabe, and
Y Kawakami, and
F Hyodoh, and
H Tsushima
January 1998,
Journal of immunology (Baltimore, Md. : 1950),
K Kinugawa, and
A Ueki, and
M Yamaguchi, and
Y Watanabe, and
Y Kawakami, and
F Hyodoh, and
H Tsushima
September 1990,
Scandinavian journal of immunology,
K Kinugawa, and
A Ueki, and
M Yamaguchi, and
Y Watanabe, and
Y Kawakami, and
F Hyodoh, and
H Tsushima
February 1993,
International journal of oncology,
K Kinugawa, and
A Ueki, and
M Yamaguchi, and
Y Watanabe, and
Y Kawakami, and
F Hyodoh, and
H Tsushima
October 1989,
European journal of immunology,
K Kinugawa, and
A Ueki, and
M Yamaguchi, and
Y Watanabe, and
Y Kawakami, and
F Hyodoh, and
H Tsushima
September 2011,
Journal of immunology (Baltimore, Md. : 1950),
K Kinugawa, and
A Ueki, and
M Yamaguchi, and
Y Watanabe, and
Y Kawakami, and
F Hyodoh, and
H Tsushima
July 1997,
Immunology,
K Kinugawa, and
A Ueki, and
M Yamaguchi, and
Y Watanabe, and
Y Kawakami, and
F Hyodoh, and
H Tsushima
October 1991,
European journal of immunology,
