Biomaterial Database

Benzoyl peroxide gel in acne therapy. 1976

E G Kuflik

A micronized benzoyl peroxide, in a magnesium aluminum silicate-alcohol gel, appears to achieve dramatic objective improvement of the comedo and papular stages of acne, as well as associated seborrhea. Burning sensations and excessive erythema, found with similar modalities, have been virtually eliminated.

UI	MeSH Term	Description	Entries
D010545	Peroxides	A group of compounds that contain a bivalent O-O group, i.e., the oxygen atoms are univalent. They can either be inorganic or organic in nature. Such compounds release atomic (nascent) oxygen readily. Thus they are strong oxidizing agents and fire hazards when in contact with combustible materials, especially under high-temperature conditions. The chief industrial uses of peroxides are as oxidizing agents, bleaching agents, and initiators of polymerization. (From Hawley's Condensed Chemical Dictionary, 11th ed)	Peroxide
D005782	Gels	Colloids with a solid continuous phase and liquid as the dispersed phase; gels may be unstable when, due to temperature or other cause, the solid phase liquefies; the resulting colloid is called a sol.
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000152	Acne Vulgaris	A chronic disorder of the pilosebaceous apparatus associated with an increase in sebum secretion. It is characterized by open comedones (blackheads), closed comedones (whiteheads), and pustular nodules. The cause is unknown, but heredity and age are predisposing factors.	Acne
D001585	Benzoyl Peroxide	A peroxide derivative that has been used topically for BURNS and as a dermatologic agent in the treatment of ACNE and POISON IVY DERMATITIS. It is used also as a bleach in the food industry.	Benzoyl Superoxide,Dibenzoyl Peroxide,Diphenylglyoxal Superoxide,PanOxyl,Peroxide, Benzoyl,Peroxide, Dibenzoyl,Superoxide, Benzoyl,Superoxide, Diphenylglyoxal