New agents labelled with technetium 99m for myocardial perfusion imaging. 1992

R Taillefer
Department of Nuclear Medicine, Hôtel-Dieu de Montréal, Que.

New agents labelled with technetium 99m (99mTc) are now available for myocardial perfusion imaging. In this article the author reviews the biologic characteristics, the imaging protocols and the clinical usefulness of thallous chloride Tl 201, 99mTc-sestamibi and 99mTc-teboroxime (not yet available in Canada), as well as their complementary roles in the detection of coronary artery disease.

UI MeSH Term Description Entries
D007267 Injections Introduction of substances into the body using a needle and syringe. Injectables,Injectable,Injection
D010091 Oximes Compounds that contain the radical R2C Aldoximes,Hydroxyimino Compounds,Ketoxime,Ketoximes,Oxime,Compounds, Hydroxyimino
D011877 Radionuclide Imaging The production of an image obtained by cameras that detect the radioactive emissions of an injected radionuclide as it has distributed differentially throughout tissues in the body. The image obtained from a moving detector is called a scan, while the image obtained from a stationary camera device is called a scintiphotograph. Gamma Camera Imaging,Radioisotope Scanning,Scanning, Radioisotope,Scintigraphy,Scintiphotography,Imaging, Gamma Camera,Imaging, Radionuclide
D002985 Clinical Protocols Precise and detailed plans for the study of a medical or biomedical problem and/or plans for a regimen of therapy. Protocols, Clinical,Research Protocols, Clinical,Treatment Protocols,Clinical Protocol,Clinical Research Protocol,Clinical Research Protocols,Protocol, Clinical,Protocol, Clinical Research,Protocols, Clinical Research,Protocols, Treatment,Research Protocol, Clinical,Treatment Protocol
D003327 Coronary Disease An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels. Coronary Heart Disease,Coronary Diseases,Coronary Heart Diseases,Disease, Coronary,Disease, Coronary Heart,Diseases, Coronary,Diseases, Coronary Heart,Heart Disease, Coronary,Heart Diseases, Coronary
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D013667 Technetium The first artificially produced element and a radioactive fission product of URANIUM. Technetium has the atomic symbol Tc, and atomic number 43. All technetium isotopes are radioactive. Technetium 99m (m Technetium 99m,99m, Technetium
D013794 Thallium Radioisotopes Unstable isotopes of thallium that decay or disintegrate emitting radiation. Tl atoms with atomic weights 198-202, 204, and 206-210 are thallium radioisotopes. Radioisotopes, Thallium
D015609 Organotechnetium Compounds Organic compounds that contain technetium as an integral part of the molecule. These compounds are often used as radionuclide imaging agents. Compounds, Organotechnetium
D017256 Technetium Tc 99m Sestamibi A technetium imaging agent used to reveal blood-starved cardiac tissue during a heart attack. 99mTc-Hexamibi,99mTc-Sestamibi,Tc MIBI,Cardiolite,Tc-99m-Methoxy-2-isobutylisonitrile,Technetium Tc 99m 2-Methoxy-2-methylpropylisonitrile,Technetium Tc 99m Sestamibi Chloride,Technetium-99m-Hexamibi,Technetium-99m-Sestamibi,99mTc Hexamibi,99mTc Sestamibi,Tc 99m Methoxy 2 isobutylisonitrile,Technetium 99m Hexamibi,Technetium 99m Sestamibi,Technetium Tc 99m 2 Methoxy 2 methylpropylisonitrile

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