Effect of thiazide diuretics on plasma volume, body electrolytes, and excretion of aldosterone in hypertension. 1961

R W GIFFORD, and V R MATTOX, and A L ORVIS, and D A SONES, and J W ROSEVEAR

UI MeSH Term Description Entries
D006973 Hypertension Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more. Blood Pressure, High,Blood Pressures, High,High Blood Pressure,High Blood Pressures
D010953 Plasma Volume Volume of PLASMA in the circulation. It is usually measured by INDICATOR DILUTION TECHNIQUES. Blood Plasma Volume,Blood Plasma Volumes,Plasma Volumes,Volume, Blood Plasma,Volume, Plasma,Volumes, Blood Plasma,Volumes, Plasma
D001810 Blood Volume Volume of circulating BLOOD. It is the sum of the PLASMA VOLUME and ERYTHROCYTE VOLUME. Blood Volumes,Volume, Blood,Volumes, Blood
D002740 Chlorothiazide A thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p812)
D004573 Electrolytes Substances that dissociate into two or more ions, to some extent, in water. Solutions of electrolytes thus conduct an electric current and can be decomposed by it (ELECTROLYSIS). (Grant & Hackh's Chemical Dictionary, 5th ed) Electrolyte
D000450 Aldosterone A hormone secreted by the ADRENAL CORTEX that regulates electrolyte and water balance by increasing the renal retention of sodium and the excretion of potassium. Aldosterone, (+-)-Isomer,Aldosterone, (11 beta,17 alpha)-Isomer
D001692 Biological Transport The movement of materials (including biochemical substances and drugs) through a biological system at the cellular level. The transport can be across cell membranes and epithelial layers. It also can occur within intracellular compartments and extracellular compartments. Transport, Biological,Biologic Transport,Transport, Biologic
D049993 Sodium Chloride Symporter Inhibitors Agents that inhibit SODIUM CHLORIDE SYMPORTERS. They act as DIURETICS. Excess use is associated with HYPOKALEMIA. Benzothiadiazine Diuretic,Potassium Depleting Diuretic,Sodium Chloride Cotransporter Inhibitor,Sodium Chloride Symporter Inhibitor,Thiazide Diuretic,Thiazide Sensitive NaCl Cotransporter Inhibitor,Benzothiadiazine Diuretics,Diuretics, Thiazide,Potassium Depleting Diuretics,Sodium Chloride Cotransporter Inhibitors,Thiazide Diuretics,Thiazide Sensitive NaCl Cotransporter Inhibitors,Depleting Diuretic, Potassium,Diuretic, Benzothiadiazine,Diuretic, Potassium Depleting,Diuretic, Thiazide,Diuretics, Benzothiadiazine,Diuretics, Potassium Depleting

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