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Synthesis of adenylyl 2,3-diphosphoglyceric acid. 1961

T HASHIMOTO, and M TATIBANA, and Y ISHII, and H YOSHIKAWA

UI MeSH Term Description Entries
D000227 Adenine Nucleotides Adenine Nucleotide,Adenosine Phosphate,Adenosine Phosphates,Nucleotide, Adenine,Nucleotides, Adenine,Phosphate, Adenosine,Phosphates, Adenosine
D019794 2,3-Diphosphoglycerate A highly anionic organic phosphate which is present in human red blood cells at about the same molar ratio as hemoglobin. It binds to deoxyhemoglobin but not the oxygenated form, therefore diminishing the oxygen affinity of hemoglobin. This is essential in enabling hemoglobin to unload oxygen in tissue capillaries. It is also an intermediate in the conversion of 3-phosphoglycerate to 2-phosphoglycerate by phosphoglycerate mutase (EC 5.4.2.1). (From Stryer Biochemistry, 4th ed, p160; Enzyme Nomenclature, 1992, p508) 2,3-Bisphosphoglycerate,2,3-DPG,2,3-Diphosphoglyceric Acid,2,3-Diphosphoglycerate, (D)-Isomer,Glycerate 2,3-Bisphosphate,2,3 Bisphosphoglycerate,2,3 Diphosphoglycerate,2,3 Diphosphoglyceric Acid,2,3-Bisphosphate, Glycerate

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[On adenylyl-2,3-diphosphoglyceric acid, a new adenine nucleotide in erythrocytes].
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Further studies on adenylyl 2, 3-diphosphoglyceric acid.
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Mechanism of action of thyroid hormones on erythrocyte 2,3-diphosphoglyceric acid synthesis.
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Synthesis of phosphonic acid isosteres of 2-phospho-, 3-phospho-, and 2,3-diphosphoglyceric acid.
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