[Alkaloids from Vinca minor L. Vincadine, minovine and vincorine].
1962
J MOKRY, and
L DUBRAVKOVA, and
P SEFCOVIC
UI
MeSH Term
Description
Entries
D000470
Alkaloids
Organic nitrogenous bases. Many alkaloids of medical importance occur in the animal and vegetable kingdoms, and some have been synthesized. (Grant & Hackh's Chemical Dictionary, 5th ed)
A group of indole-indoline dimers which are ALKALOIDS obtained from the VINCA genus of plants. They inhibit polymerization of TUBULIN into MICROTUBULES thus blocking spindle formation and arresting cells in METAPHASE. They are some of the most useful ANTINEOPLASTIC AGENTS.