The estimation of red cell volume with 51Cr-labelled erythrocytes and plasma volume with radioiodinated human serum albumin. 1962

D HART, and J METZ

The validity of a simplified procedure for the direct estimation of both red cell and plasma volume, using (51)Cr-labelled erythrocytes and radioiodinated human serum albumin, has been examined. It is suggested that the procedure, involving three venepunctures only, will yield accurate measurements of both compartments.

UI MeSH Term Description Entries
D007700 Kinetics The rate dynamics in chemical or physical systems.
D010953 Plasma Volume Volume of PLASMA in the circulation. It is usually measured by INDICATOR DILUTION TECHNIQUES. Blood Plasma Volume,Blood Plasma Volumes,Plasma Volumes,Volume, Blood Plasma,Volume, Plasma,Volumes, Blood Plasma,Volumes, Plasma
D001811 Blood Volume Determination Method for determining the circulating blood volume by introducing a known quantity of foreign substance into the blood and determining its concentration some minutes later when thorough mixing has occurred. From these two values the blood volume can be calculated by dividing the quantity of injected material by its concentration in the blood at the time of uniform mixing. Generally expressed as cubic centimeters or liters per kilogram of body weight. Blood Volume Determinations,Determination, Blood Volume,Determinations, Blood Volume,Volume Determination, Blood,Volume Determinations, Blood
D002859 Chromium Isotopes Stable chromium atoms that have the same atomic number as the element chromium, but differ in atomic weight. Cr-50, 53, and 54 are stable chromium isotopes. Isotopes, Chromium
D004912 Erythrocytes Red blood cells. Mature erythrocytes are non-nucleated, biconcave disks containing HEMOGLOBIN whose function is to transport OXYGEN. Blood Cells, Red,Blood Corpuscles, Red,Red Blood Cells,Red Blood Corpuscles,Blood Cell, Red,Blood Corpuscle, Red,Erythrocyte,Red Blood Cell,Red Blood Corpuscle
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012709 Serum Albumin A major protein in the BLOOD. It is important in maintaining the colloidal osmotic pressure and transporting large organic molecules. Plasma Albumin,Albumin, Serum
D012711 Serum Albumin, Radio-Iodinated Normal human serum albumin mildly iodinated with radioactive iodine (131-I) which has a half-life of 8 days, and emits beta and gamma rays. It is used as a diagnostic aid in blood volume determination. (from Merck Index, 11th ed) (131)I-MAA,(131)I-Macroaggregated Albumin,Serum Albumin, Radioiodinated,Albumin, Radio-Iodinated Serum,Albumin, Radioiodinated Serum,Radio-Iodinated Serum Albumin,Radioiodinated Serum Albumin,Serum Albumin, Radio Iodinated
D048429 Cell Size The quantity of volume or surface area of CELLS. Cell Volume,Cell Sizes,Cell Volumes,Size, Cell,Sizes, Cell,Volume, Cell,Volumes, Cell

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