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Three monoclonal antibodies which recognize rabbit leucocytes have been characterized by immunofluorescence staining of a variety of cell populations and also by immunochemical techniques. The evidence obtained suggests that these antibodies recognize the rabbit equivalents of the CD58/LFA-3 (VC21), CD43/leukosialin (L11/135) and CD9 (MM2/57) antigens. A fourth antibody, RPN3/57, recognizes an antigen expressed strongly on T cells, thymocytes and neutrophils and at lower levels on platelets. It has not, however been possible to characterize the antigen recognized by RPN3/57 in molecular terms. Both L11/135 and RPN3/57 are useful reagents for the detection of T cells both by flow cytometry and by immunohistochemistry.
J M Wilkinson, and
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R A Sellars, and
C Boniface
December 1988,
Cancer research,
J M Wilkinson, and
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C Boniface
June 1983,
Biochemical Society transactions,
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Immunology today,
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Parasite immunology,
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May 1994,
Annals of surgical oncology,
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May 1989,
Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society,
J M Wilkinson, and
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June 1985,
Journal of biological response modifiers,
J M Wilkinson, and
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Ciba Foundation symposium,
J M Wilkinson, and
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J M Wilkinson, and
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C Boniface
June 1999,
Parasitology research,
