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The humoral inter-alpha-trypsin inhibitor is to define as precursor of the acid stable trypsin-plasmin-inhibitor in the serum. The inhibitor is filtrated by the glomerulum and excreted in the urine. The serum level of the inhibitor is increased in nephropathy. Using a new assay for the intact precursor it was found that during inflammation the decreased precursor level indicates an increased turnover, though the glomerular filtration of the acid-stable inhibitor is within normal range. The increase of the precursor level during nephropathy indicates that the kidney is the main degradation organe for the inter-alpha-trypsin inhibitor. Nevertheless, an increase of the acid-stable inhibitor is to be seen. This fact is only to explain if it is assumed that the inter-alpha-trypsin inhibitor is permanently degraded everywhere in the organism.
K Hochstrasser, and
J Niebel, and
H Feuth, and
K Lempart
December 1977,
Pathologie-biologie,
K Hochstrasser, and
J Niebel, and
H Feuth, and
K Lempart
February 1976,
Hoppe-Seyler's Zeitschrift fur physiologische Chemie,
K Hochstrasser, and
J Niebel, and
H Feuth, and
K Lempart
October 1979,
Nihon Kyobu Shikkan Gakkai zasshi,
K Hochstrasser, and
J Niebel, and
H Feuth, and
K Lempart
August 1977,
Klinische Wochenschrift,
K Hochstrasser, and
J Niebel, and
H Feuth, and
K Lempart
January 1966,
Voprosy meditsinskoi khimii,
K Hochstrasser, and
J Niebel, and
H Feuth, and
K Lempart
January 1978,
Respiration; international review of thoracic diseases,
K Hochstrasser, and
J Niebel, and
H Feuth, and
K Lempart
January 1987,
Padiatrie und Grenzgebiete,
K Hochstrasser, and
J Niebel, and
H Feuth, and
K Lempart
July 1988,
Biochimica et biophysica acta,
K Hochstrasser, and
J Niebel, and
H Feuth, and
K Lempart
September 1979,
Hoppe-Seyler's Zeitschrift fur physiologische Chemie,
K Hochstrasser, and
J Niebel, and
H Feuth, and
K Lempart
June 1980,
Nihon Ketsueki Gakkai zasshi : journal of Japan Haematological Society,
