BIOMAT Database Logo BIOMAT Database Logo

Oxidative biotransformation of di-n-butylnitrosamine. Formation in vitro of aldehydes in the presence of rat liver microsomes. 1977

L Blattmann, and R Preussmann

After in vitro incubation of di-n-butylnitrosamine with rat liver microsomes in the presence of the necessary cofactors butyraldehyde has been identified as a reaction product together with smaller amounts of propionaldehyde and acetaldehyde.

UI MeSH Term Description Entries
D008862 Microsomes, Liver Closed vesicles of fragmented endoplasmic reticulum created when liver cells or tissue are disrupted by homogenization. They may be smooth or rough. Liver Microsomes,Liver Microsome,Microsome, Liver
D009602 Nitrosamines A class of compounds that contain a -NH2 and a -NO radical. Many members of this group have carcinogenic and mutagenic properties. Nitrosamine
D010084 Oxidation-Reduction A chemical reaction in which an electron is transferred from one molecule to another. The electron-donating molecule is the reducing agent or reductant; the electron-accepting molecule is the oxidizing agent or oxidant. Reducing and oxidizing agents function as conjugate reductant-oxidant pairs or redox pairs (Lehninger, Principles of Biochemistry, 1982, p471). Redox,Oxidation Reduction
D006900 Hydroxylation Placing of a hydroxyl group on a compound in a position where one did not exist before. (Stedman, 26th ed) Hydroxylations
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D051381 Rats The common name for the genus Rattus. Rattus,Rats, Laboratory,Rats, Norway,Rattus norvegicus,Laboratory Rat,Laboratory Rats,Norway Rat,Norway Rats,Rat,Rat, Laboratory,Rat, Norway,norvegicus, Rattus
D066298 In Vitro Techniques Methods to study reactions or processes taking place in an artificial environment outside the living organism. In Vitro Test,In Vitro Testing,In Vitro Tests,In Vitro as Topic,In Vitro,In Vitro Technique,In Vitro Testings,Technique, In Vitro,Techniques, In Vitro,Test, In Vitro,Testing, In Vitro,Testings, In Vitro,Tests, In Vitro,Vitro Testing, In

Related Publications

L Blattmann, and R Preussmann
Biotransformation of myrislignan by rat liver microsomes in vitro.
February 2008, Phytochemistry,
L Blattmann, and R Preussmann
In vitro biotransformation of flavonoids by rat liver microsomes.
April 1998, Xenobiotica; the fate of foreign compounds in biological systems,
L Blattmann, and R Preussmann
[Liver and bladder carcinomas in the guinea pig following di-n-butylnitrosamine administration].
January 1968, Zeitschrift fur Krebsforschung,
L Blattmann, and R Preussmann
[Oxidative biotransformation of clotepins (octoclothepin) in liver microsomes].
December 1979, Die Pharmazie,
L Blattmann, and R Preussmann
In vitro biotransformation of thiazopyr by rat liver microsomes: oxidative cleavage of a carboxylic methylester by monooxygenases.
August 1994, Xenobiotica; the fate of foreign compounds in biological systems,
L Blattmann, and R Preussmann
Oxidative demethylation of N-methylhydrazines by rat liver microsomes.
November 1969, Archives of biochemistry and biophysics,
L Blattmann, and R Preussmann
Nicotinamide N-oxide formation by rat liver microsomes.
March 1983, Biochemical pharmacology,
L Blattmann, and R Preussmann
Biotransformation of demecolcine by rat liver microsomes.
January 1988, Acta Universitatis Palackianae Olomucensis Facultatis Medicae,
L Blattmann, and R Preussmann
Oxidative and reductive biotransformation of chloroform in mouse liver microsomes.
January 1987, Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement,
L Blattmann, and R Preussmann
Di-n-butyltindichloride uncouples oxidative phosphorylation in rat liver mitochondria.
August 1983, Toxicology and applied pharmacology,
Copied contents to your clipboard!