-transparent.png){kind=logo}
The 4D1D4 hybridoma cells were derived from the fusion of spleen cells from BALB/c nude mice with NS-1 mouse myeloma cells. The surface phenotypes of 4D1D4 hybridoma cells were Thy-1.2+, L3T4 (CD4)-, Lyt-2 (CD8)-, Asialo GM1+ and p-55 interleukin-2 (IL-2) receptor (CD25)-. This phenotypic pattern was consistent with the surface phenotype of NK cells. The 4D1D4 cells showed the definite killer activity against a syngenic tumor cell line, RL male-1, but not against an allogenic YAC-1 line. The killer activity of the 4D1D4 cells was not affected by the addition of exogenous IL-2. It was, therefore, suggested that 4D1D4 cells might be representative of resting NK cells with expression of no functional IL-2 receptors. The hybridoma technology might be useful for establishment of the cloned NK cells.
Y Suzuki, and
M Funabashi, and
S Isomura, and
K Yoshikawa, and
K Notake, and
T Yokochi
March 1997,
Nihon rinsho. Japanese journal of clinical medicine,
Y Suzuki, and
M Funabashi, and
S Isomura, and
K Yoshikawa, and
K Notake, and
T Yokochi
March 1982,
European journal of immunology,
Y Suzuki, and
M Funabashi, and
S Isomura, and
K Yoshikawa, and
K Notake, and
T Yokochi
January 1981,
Progress in clinical and biological research,
Y Suzuki, and
M Funabashi, and
S Isomura, and
K Yoshikawa, and
K Notake, and
T Yokochi
May 1984,
Lijecnicki vjesnik,
Y Suzuki, and
M Funabashi, and
S Isomura, and
K Yoshikawa, and
K Notake, and
T Yokochi
August 1991,
Veterinary immunology and immunopathology,
Y Suzuki, and
M Funabashi, and
S Isomura, and
K Yoshikawa, and
K Notake, and
T Yokochi
January 1987,
Immunogenetics,
Y Suzuki, and
M Funabashi, and
S Isomura, and
K Yoshikawa, and
K Notake, and
T Yokochi
December 1982,
Immunobiology,
Y Suzuki, and
M Funabashi, and
S Isomura, and
K Yoshikawa, and
K Notake, and
T Yokochi
January 1983,
International journal of tissue reactions,
Y Suzuki, and
M Funabashi, and
S Isomura, and
K Yoshikawa, and
K Notake, and
T Yokochi
April 1983,
Casopis lekaru ceskych,
Y Suzuki, and
M Funabashi, and
S Isomura, and
K Yoshikawa, and
K Notake, and
T Yokochi
February 2000,
The Journal of experimental medicine,
