Biomaterial Database

Toxicity of methyl methacrylate monomer in orbital and cranial surgery. 1992

R E Wesley, and J D Brinsko

Department of Ophthalmology, Vanderbilt University Medical Center, Nashville, Tennessee.

Methyl methacrylate (plastic bone cement) can be prepared by mixing a vial of liquid monomer with a powder. The monomer can release a toxic vapor. We measured the exposure of operating room personnel to this toxic substance. We believe that an awareness of the potential toxicity of the monomer is important and that devices to limit its exposure to personnel should be used in operating rooms.

UI	MeSH Term	Description	Entries
D008768	Methylmethacrylates	The methyl esters of methacrylic acid that polymerize easily and are used as tissue cements, dental materials, and absorbent for biological substances.
D009873	Operating Rooms	Facilities equipped for performing surgery.	Operating Room,Room, Operating,Rooms, Operating
D009915	Orbit	Bony cavity that holds the eyeball and its associated tissues and appendages.	Eye Socket,Eye Sockets,Orbits,Socket, Eye,Sockets, Eye
D010564	Personnel, Hospital	The individuals employed by the hospital.	Hospital Personnel
D001843	Bone Cements	Adhesives used to fix prosthetic devices to bones and to cement bone to bone in difficult fractures. Synthetic resins are commonly used as cements. A mixture of monocalcium phosphate, monohydrate, alpha-tricalcium phosphate, and calcium carbonate with a sodium phosphate solution is also a useful bone paste.	Bone Cement,Bone Glues,Bone Pastes,Bone Glue,Bone Paste,Cement, Bone,Cements, Bone,Glue, Bone,Glues, Bone,Paste, Bone,Pastes, Bone
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000395	Air Pollutants, Occupational	Toxic air-borne matter related to work performed They are usually produced by the specific nature of the occupation.	Occupational Air Pollutants,Pollutants, Occupational Air
D012886	Skull	The SKELETON of the HEAD including the FACIAL BONES and the bones enclosing the BRAIN.	Calvaria,Cranium,Calvarium,Skulls
D016273	Occupational Exposure	The exposure to potentially harmful chemical, physical, or biological agents that occurs as a result of one's occupation.	Exposure, Occupational,Exposures, Occupational,Occupational Exposures
D020366	Methylmethacrylate	The methyl ester of methacrylic acid. It polymerizes easily to form POLYMETHYL METHACRYLATE. It is used as a bone cement.	Methylmethacrylate Methyl Monomer,Cranioplast,Kallocryl,Kallocryl A,Metaplex,Methacrylate Methyl Monomer,Simplex P,Sintex,Zimmer Bone Cement,Bone Cement, Zimmer,Bone Cements, Zimmer,Cement, Zimmer Bone,Cements, Zimmer Bone,Cranioplasts,Kallocryls,Metaplices,Methacrylate Methyl Monomers,Methyl Monomer, Methacrylate,Methyl Monomer, Methylmethacrylate,Methyl Monomers, Methacrylate,Methyl Monomers, Methylmethacrylate,Methylmethacrylate Methyl Monomers,Monomer, Methacrylate Methyl,Monomer, Methylmethacrylate Methyl,Monomers, Methacrylate Methyl,Monomers, Methylmethacrylate Methyl,Sintices,Zimmer Bone Cements