Further controlled evaluations of fenbendazole as a bovine anthelmintic. 1977

J W Crowley, and W J Foreyt, and D H Bliss, and A C Todd

The efficacy of fenbendazole (methyl-5-(phenythio)-2-benzimidazole-carbamate) in cattle parasitized by the lungworm Dictyocaulus viviparus and in other cattle parasitized by Haemonchus, Ostertagia, Trichostrongylus, Cooperia, and Oesophagostomum was investigated in 3 controlled critical experiments. A single treatment with 5.0 mg/kg of body weight administered in the feed or in a 10% suspension exceeded 99% efficacy against these helminths. Dosages of 1, 0.5, 0.35, and 0.25 mg/kg of body weight administered for 5 days to individual calves in their feed were 99% efficacious against all helminths, except Haemonchus. The 1.0 mg/kg dose removed 99.5% of the Haemonchus, and the other 3 dosages had efficacies of 91.0, 93.7, and 95.6%, respectively. The small daily dosages were not evaluated against Dictyocaulus.

UI MeSH Term Description Entries
D009349 Nematode Infections Infections by nematodes, general or unspecified. Infections, Nematode,Infection, Nematode,Nematode Infection
D009814 Oesophagostomiasis Infection of the intestinal tract with worms of the genus OESOPHAGOSTOMUM. This condition occurs mainly in animals other than man. Oesophagostomiases
D010029 Ostertagiasis A disease of herbivorous mammals, particularly cattle and sheep, caused by stomach worms of the genus OSTERTAGIA. Ostertagiases
D002417 Cattle Domesticated bovine animals of the genus Bos, usually kept on a farm or ranch and used for the production of meat or dairy products or for heavy labor. Beef Cow,Bos grunniens,Bos indicus,Bos indicus Cattle,Bos taurus,Cow,Cow, Domestic,Dairy Cow,Holstein Cow,Indicine Cattle,Taurine Cattle,Taurus Cattle,Yak,Zebu,Beef Cows,Bos indicus Cattles,Cattle, Bos indicus,Cattle, Indicine,Cattle, Taurine,Cattle, Taurus,Cattles, Bos indicus,Cattles, Indicine,Cattles, Taurine,Cattles, Taurus,Cow, Beef,Cow, Dairy,Cow, Holstein,Cows,Dairy Cows,Domestic Cow,Domestic Cows,Indicine Cattles,Taurine Cattles,Taurus Cattles,Yaks,Zebus
D002418 Cattle Diseases Diseases of domestic cattle of the genus Bos. It includes diseases of cows, yaks, and zebus. Bovine Diseases,Bovine Disease,Cattle Disease,Disease, Bovine,Disease, Cattle,Diseases, Bovine,Diseases, Cattle
D004022 Dictyocaulus Infections Infection with nematodes of the genus DICTYOCAULUS. In deer, cattle, sheep, and horses the bronchi are the site of infestation. Dictyocauliasis,Infections, Dictyocaulus,Dictyocauliases,Dictyocaulus Infection,Infection, Dictyocaulus
D004341 Drug Evaluation Any process by which toxicity, metabolism, absorption, elimination, preferred route of administration, safe dosage range, etc., for a drug or group of drugs is determined through clinical assessment in humans or veterinary animals. Evaluation Studies, Drug,Drug Evaluation Studies,Drug Evaluation Study,Drug Evaluations,Evaluation Study, Drug,Evaluation, Drug,Evaluations, Drug,Studies, Drug Evaluation,Study, Drug Evaluation
D005243 Feces Excrement from the INTESTINES, containing unabsorbed solids, waste products, secretions, and BACTERIA of the DIGESTIVE SYSTEM.
D005273 Fenbendazole Antinematodal benzimidazole used in veterinary medicine. Panacur,Phenbendasol
D006188 Haemonchiasis Infection with nematodes of the genus HAEMONCHUS, characterized by digestive abnormalities and anemia similar to that from hookworm infestation. Haemonchiases

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