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A survey is given of the karyotypes observed in 362 children clinically diagnosed as cases of Down's syndrome from whom material was sent to 8 collaborating cytogenic laboratories in Hungary during the period 1965-1974. The sample studied cytogenetically constitutes about 20% of all children born in Hungary in this decade with Down's syndrome. The ways in which patients were selected for cytogenetic examinations could not be specified. In the sample, standard trisomy 21 was found in 91.7%, translocations in 3.9% and mosaicism in 4.4%. The mean age of the mothers of the children investigated was 29.05 years, a relatively low figure which may be explained by the decrease of the mean maternal age over the last decades.
Z Papp, and
M Osztovics, and
D Schuler, and
K Méhes, and
E Czeizel, and
L Horváth, and
G Szemere, and
J László
January 1976,
Orvosi hetilap,
Z Papp, and
M Osztovics, and
D Schuler, and
K Méhes, and
E Czeizel, and
L Horváth, and
G Szemere, and
J László
December 1969,
Journal of medical genetics,
Z Papp, and
M Osztovics, and
D Schuler, and
K Méhes, and
E Czeizel, and
L Horváth, and
G Szemere, and
J László
January 1988,
Acta morphologica Hungarica,
Z Papp, and
M Osztovics, and
D Schuler, and
K Méhes, and
E Czeizel, and
L Horváth, and
G Szemere, and
J László
April 1970,
Ceskoslovenska pediatrie,
Z Papp, and
M Osztovics, and
D Schuler, and
K Méhes, and
E Czeizel, and
L Horváth, and
G Szemere, and
J László
August 1979,
Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association,
Z Papp, and
M Osztovics, and
D Schuler, and
K Méhes, and
E Czeizel, and
L Horváth, and
G Szemere, and
J László
November 1978,
Nigerian medical journal : journal of the Nigeria Medical Association,
Z Papp, and
M Osztovics, and
D Schuler, and
K Méhes, and
E Czeizel, and
L Horváth, and
G Szemere, and
J László
February 1968,
Saishin igaku. Modern medicine,
Z Papp, and
M Osztovics, and
D Schuler, and
K Méhes, and
E Czeizel, and
L Horváth, and
G Szemere, and
J László
February 1977,
Pediatria polska,
Z Papp, and
M Osztovics, and
D Schuler, and
K Méhes, and
E Czeizel, and
L Horváth, and
G Szemere, and
J László
January 1970,
Humangenetik,
Z Papp, and
M Osztovics, and
D Schuler, and
K Méhes, and
E Czeizel, and
L Horváth, and
G Szemere, and
J László
June 1976,
Journal of mental deficiency research,
