Biomaterial Database

[Tropical malaria and sickle-cell anemia: a tropical surprise]. 1992

J B Boringa, and G M de Jong

Westeinde Ziekenhuis, Den Haag.

A case of a very sick 2.5-year-old, Ghanese boy with fever, who fell in coma in the emergency room, is described. He was diagnosed as having blackwater fever (BWF) on clinical grounds. He also had a sickle cell anaemia. A short review of BWF is given and we discuss possible causes of the anaemia in this case. The anaemia in sickle cell anaemia is described and it appears that malaria tropica can lead to a severe hemolytic sickle cell crises. We discuss the combination of sickle cell anaemia and malaria tropica.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D001742	Blackwater Fever	A complication of MALARIA, FALCIPARUM characterized by the passage of dark red to black urine.	Malaria, Hemolytic,Black Water Fever,Black Water Fevers,Blackwater Fevers,Fever, Black Water,Fever, Blackwater,Fevers, Black Water,Fevers, Blackwater,Hemolytic Malaria,Hemolytic Malarias,Malarias, Hemolytic
D001803	Blood Transfusion	The introduction of whole blood or blood component directly into the blood stream. (Dorland, 27th ed)	Blood Transfusions,Transfusion, Blood,Transfusions, Blood
D002675	Child, Preschool	A child between the ages of 2 and 5.	Children, Preschool,Preschool Child,Preschool Children
D006451	Hemoglobin, Sickle	An abnormal hemoglobin resulting from the substitution of valine for glutamic acid at position 6 of the beta chain of the globin moiety. The heterozygous state results in sickle cell trait, the homozygous in sickle cell anemia.	Hemoglobin S,Deoxygenated Sickle Hemoglobin,Deoxyhemoglobin S,Hemoglobin SS,Hemoglobin, Deoxygenated Sickle,SS, Hemoglobin,Sickle Hemoglobin,Sickle Hemoglobin, Deoxygenated
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000755	Anemia, Sickle Cell	A disease characterized by chronic hemolytic anemia, episodic painful crises, and pathologic involvement of many organs. It is the clinical expression of homozygosity for hemoglobin S.	Hemoglobin S Disease,HbS Disease,Sickle Cell Anemia,Sickle Cell Disease,Sickle Cell Disorders,Sickling Disorder Due to Hemoglobin S,Anemias, Sickle Cell,Cell Disease, Sickle,Cell Diseases, Sickle,Cell Disorder, Sickle,Cell Disorders, Sickle,Disease, Hemoglobin S,Hemoglobin S Diseases,Sickle Cell Anemias,Sickle Cell Diseases,Sickle Cell Disorder
D017707	Erythrocyte Transfusion	The transfer of erythrocytes from a donor to a recipient or reinfusion to the donor.	Red Blood Cell Transfusion,Red Blood Cell Transfusions,Transfusion, Red Blood Cell,Transfusions, Red Blood Cell,Erythrocyte Transfusions,Transfusion, Erythrocyte,Transfusions, Erythrocyte