BIOMAT Database Logo BIOMAT Database Logo

A second gene for a secreted aspartate proteinase in Candida albicans. 1992

R J Wright, and A Carne, and A D Hieber, and I L Lamont, and G W Emerson, and P A Sullivan
Department of Biochemistry, University of Otago, Dunedin, New Zealand.

The gene (PRA11) encoding a secreted aspartate proteinase of Candida albicans has been cloned and sequenced. The nucleotide and deduced amino acid sequences of PRA11 are 77 and 73% identical, respectively, with the reported sequences of PRA10 also cloned from C. albicans. Southern analyses indicated that the genome of each strain examined (ATCC 10231 and ATCC 10261) contains PRA10 and PRA11. Northern (RNA) analyses showed that PRA11 was expressed at a much higher level than was PRA10 when secretion of the proteinase by strain ATCC 10261 was induced with albumin.

UI MeSH Term Description Entries
D008969 Molecular Sequence Data Descriptions of specific amino acid, carbohydrate, or nucleotide sequences which have appeared in the published literature and/or are deposited in and maintained by databanks such as GENBANK, European Molecular Biology Laboratory (EMBL), National Biomedical Research Foundation (NBRF), or other sequence repositories. Sequence Data, Molecular,Molecular Sequencing Data,Data, Molecular Sequence,Data, Molecular Sequencing,Sequencing Data, Molecular
D002176 Candida albicans A unicellular budding fungus which is the principal pathogenic species causing CANDIDIASIS (moniliasis). Candida albicans var. stellatoidea,Candida stellatoidea,Dematium albicans,Monilia albicans,Myceloblastanon albicans,Mycotorula albicans,Parasaccharomyces albicans,Procandida albicans,Procandida stellatoidea,Saccharomyces albicans,Syringospora albicans
D003001 Cloning, Molecular The insertion of recombinant DNA molecules from prokaryotic and/or eukaryotic sources into a replicating vehicle, such as a plasmid or virus vector, and the introduction of the resultant hybrid molecules into recipient cells without altering the viability of those cells. Molecular Cloning
D005800 Genes, Fungal The functional hereditary units of FUNGI. Fungal Genes,Fungal Gene,Gene, Fungal
D000595 Amino Acid Sequence The order of amino acids as they occur in a polypeptide chain. This is referred to as the primary structure of proteins. It is of fundamental importance in determining PROTEIN CONFORMATION. Protein Structure, Primary,Amino Acid Sequences,Sequence, Amino Acid,Sequences, Amino Acid,Primary Protein Structure,Primary Protein Structures,Protein Structures, Primary,Structure, Primary Protein,Structures, Primary Protein
D001483 Base Sequence The sequence of PURINES and PYRIMIDINES in nucleic acids and polynucleotides. It is also called nucleotide sequence. DNA Sequence,Nucleotide Sequence,RNA Sequence,DNA Sequences,Base Sequences,Nucleotide Sequences,RNA Sequences,Sequence, Base,Sequence, DNA,Sequence, Nucleotide,Sequence, RNA,Sequences, Base,Sequences, DNA,Sequences, Nucleotide,Sequences, RNA
D016282 Aspartic Acid Endopeptidases A sub-subclass of endopeptidases that depend on an ASPARTIC ACID residue for their activity. Aspartic Endopeptidases,Aspartyl Endopeptidases,Acid Endopeptidases, Aspartic,Endopeptidases, Aspartic Acid,Endopeptidases, Aspartyl
D016681 Genome, Fungal The complete gene complement contained in a set of chromosomes in a fungus. Fungal Genome,Fungal Genomes,Genomes, Fungal
D017386 Sequence Homology, Amino Acid The degree of similarity between sequences of amino acids. This information is useful for the analyzing genetic relatedness of proteins and species. Homologous Sequences, Amino Acid,Amino Acid Sequence Homology,Homologs, Amino Acid Sequence,Homologs, Protein Sequence,Homology, Protein Sequence,Protein Sequence Homologs,Protein Sequence Homology,Sequence Homology, Protein,Homolog, Protein Sequence,Homologies, Protein Sequence,Protein Sequence Homolog,Protein Sequence Homologies,Sequence Homolog, Protein,Sequence Homologies, Protein,Sequence Homologs, Protein

Related Publications

R J Wright, and A Carne, and A D Hieber, and I L Lamont, and G W Emerson, and P A Sullivan
Evidence for a role for secreted aspartate proteinase of Candida albicans in vulvovaginal candidiasis.
June 1990, The Journal of infectious diseases,
R J Wright, and A Carne, and A D Hieber, and I L Lamont, and G W Emerson, and P A Sullivan
The secreted aspartate proteinase of Candida albicans: physiology of secretion and virulence of a proteinase-deficient mutant.
April 1990, Journal of general microbiology,
R J Wright, and A Carne, and A D Hieber, and I L Lamont, and G W Emerson, and P A Sullivan
Sequence of the Candida albicans gene encoding the secretory aspartate proteinase.
January 1991, Journal of medical and veterinary mycology : bi-monthly publication of the International Society for Human and Animal Mycology,
R J Wright, and A Carne, and A D Hieber, and I L Lamont, and G W Emerson, and P A Sullivan
Secreted aspartic proteinase from Candida albicans acts as a chemoattractant for peripheral neutrophils.
November 2013, Journal of dermatological science,
R J Wright, and A Carne, and A D Hieber, and I L Lamont, and G W Emerson, and P A Sullivan
cDNA cloning of an aspartic proteinase secreted by Candida albicans.
January 1992, Microbiology and immunology,
R J Wright, and A Carne, and A D Hieber, and I L Lamont, and G W Emerson, and P A Sullivan
Expression of Candida albicans secreted aspartyl proteinase in acute vaginal candidiasis.
June 2007, Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban,
R J Wright, and A Carne, and A D Hieber, and I L Lamont, and G W Emerson, and P A Sullivan
Profile of Candida albicans-secreted aspartic proteinase elicited during vaginal infection.
March 2005, Infection and immunity,
R J Wright, and A Carne, and A D Hieber, and I L Lamont, and G W Emerson, and P A Sullivan
Differential expression of Candida albicans secreted aspartyl proteinase in human vulvovaginal candidiasis.
September 2007, Mycoses,
R J Wright, and A Carne, and A D Hieber, and I L Lamont, and G W Emerson, and P A Sullivan
Upregulation of secreted aspartyl proteinase genes of fluconazole-sensitive Candida albicans isolates.
December 2019, Molecular biology reports,
R J Wright, and A Carne, and A D Hieber, and I L Lamont, and G W Emerson, and P A Sullivan
Quantitative expression of the Candida albicans secreted aspartyl proteinase gene family in human oral and vaginal candidiasis.
November 2008, Microbiology (Reading, England),
Copied contents to your clipboard!