[NeuFlex Silastic implant in metacarpophalangeal joint arthroplasty]. 2003

A Erdogan, and A P C Weiss
Departement of Orthopaedics, Brown Medical School, Rhode Island Hospital, Providence, RI 02905, USA.

The NeuFlex joint implant is, like the Swanson prosthesis, a silicone-spacer-implant for metacarpophalangeal arthroplasty in rheumatoid arthritis or osteoarthritis. The implant design differs essentially through a preformed, 30 degrees anatomically neutral angle and palmar lying movement center, which reduces strain across the hinge by 35%. The Swanson prosthesis is straight with a dorsal lying movement center. The advantage of this new design is an improved overall function arc and range of movement in the MCP-joint with a better grip-function. Results of simulator and laboratory tests are presented and interpreted. In 50 patients (168 MCP-joints), early results show an average functional arc of movement of 61 degrees and an average extensor lag of 12 degrees. The 30 degrees pre-bend angle, corresponding to the normal resting angle of the hand, and the improved flexor tendon excursion and moment arm appear to be the main reasons for the substantially improved flexion following use of the NeuFlex device.

UI MeSH Term Description Entries
D007592 Joint Diseases Diseases involving the JOINTS. Arthropathies,Arthropathy,Joint Disease
D007595 Joint Prosthesis Prostheses used to partially or totally replace a human or animal joint. (from UMDNS, 1999) Joint Prostheses,Prostheses, Joint,Prosthesis, Joint
D008662 Metacarpophalangeal Joint The articulation between a metacarpal bone and a phalanx. Joint, Metacarpophalangeal,Joints, Metacarpophalangeal,Metacarpophalangeal Joints
D011474 Prosthesis Design The plan and delineation of prostheses in general or a specific prosthesis. Design, Prosthesis,Designs, Prosthesis,Prosthesis Designs
D002986 Clinical Trials as Topic Works about pre-planned studies of the safety, efficacy, or optimum dosage schedule (if appropriate) of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. This concept includes clinical trials conducted both in the U.S. and in other countries. Clinical Trial as Topic
D004129 Dimethylpolysiloxanes Silicone polymers which consist of silicon atoms substituted with methyl groups and linked by oxygen atoms. They comprise a series of biocompatible materials used as liquids, gels or solids; as film for artificial membranes, gels for implants, and liquids for drug vehicles; and as antifoaming agents. Dimethylsiloxanes,Polydimethylsiloxanes,Dimethylpolysiloxane,Dimethylsiloxane
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001172 Arthritis, Rheumatoid A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated. Rheumatoid Arthritis
D001178 Arthroplasty Surgical reconstruction of a joint to relieve pain or restore motion. Bone Tunnel Enlargement,Bone Tunnel Widening,Arthroplasties,Bone Tunnel Enlargements,Bone Tunnel Widenings,Enlargement, Bone Tunnel,Tunnel Enlargement, Bone,Tunnel Widening, Bone,Widening, Bone Tunnel
D012828 Silicones A broad family of synthetic organosiloxane polymers containing a repeating silicon-oxygen backbone with organic side groups attached via carbon-silicon bonds. Depending on their structure, they are classified as liquids, gels, and elastomers. (From Merck Index, 12th ed) Silicone

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