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Palatine tonsils play an important role in the development of the immune system, being the first organ in the lymph system which analyses and reacts to antigenic stimulation. In this study, the peritonsillar area of Waldeyer's ring was investigated in 88 normal human embryos which were examined histologically and immunohistochemically. The progressive development of palatine tonsils during embryonic life is discussed. The first appearance of tonsils is in about the 14th-15th week followed by a parallel development of B- and T-cell regions which accounts for the high incidence of non mucosa-associated lymphoid tissue lymphomas among all tonsillar lymphomas and the higher incidence of T-cell-lymphomas, in comparison to the mucosa-associated lymphoid tissue of the digestive system. The way in which the human body develops the palatine tonsils quickly and prepares them to react to the first antigenic stimulation, are discussed.
G Noussios, and
J Xanthopoulos, and
T Zaraboukas, and
V Vital, and
I Konstantinidis
February 2000,
Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale,
G Noussios, and
J Xanthopoulos, and
T Zaraboukas, and
V Vital, and
I Konstantinidis
January 1971,
Zhurnal ushnykh, nosovykh i gorlovykh boleznei = The journal of otology, rhinology, and laryngologie [sic],
G Noussios, and
J Xanthopoulos, and
T Zaraboukas, and
V Vital, and
I Konstantinidis
January 2006,
Vestnik otorinolaringologii,
G Noussios, and
J Xanthopoulos, and
T Zaraboukas, and
V Vital, and
I Konstantinidis
July 1989,
Nihon Jibiinkoka Gakkai kaiho,
G Noussios, and
J Xanthopoulos, and
T Zaraboukas, and
V Vital, and
I Konstantinidis
January 1974,
Zhurnal ushnykh, nosovykh i gorlovykh boleznei = The journal of otology, rhinology, and laryngologie [sic],
G Noussios, and
J Xanthopoulos, and
T Zaraboukas, and
V Vital, and
I Konstantinidis
May 1971,
Nihon Jibiinkoka Gakkai kaiho,
G Noussios, and
J Xanthopoulos, and
T Zaraboukas, and
V Vital, and
I Konstantinidis
June 1981,
Ceskoslovenska otolaryngologie,
G Noussios, and
J Xanthopoulos, and
T Zaraboukas, and
V Vital, and
I Konstantinidis
January 1976,
Vestnik otorinolaringologii,
G Noussios, and
J Xanthopoulos, and
T Zaraboukas, and
V Vital, and
I Konstantinidis
January 1960,
Vestnik otorinolaringologii,
G Noussios, and
J Xanthopoulos, and
T Zaraboukas, and
V Vital, and
I Konstantinidis
January 1970,
Zhurnal ushnykh, nosovykh i gorlovykh boleznei = The journal of otology, rhinology, and laryngologie [sic],
