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Synthesis of new homo and heterodimers of 2',3'-dideoxyinosine (ddI) using ester linkages. 2003
L Ait Mohamed, and
M Taourirte, and
A Rochdi, and
H B Lazrek, and
J J Vasseur, and
J W Engels, and
C Pannecouque, and
E De Clercq
Laboratoire de Chimie Bio-Organique, Faculté des Sciences, Semlalia, Marrakech, Morocco.
A series of new homo and heterodimers of ddI has been synthesized. A glutarate diester spacer was used to covalently couple ddI onto ddI, AZT or d4T.
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