Effects of pupil diameter on light detection and temporal modulation. 2003

Rachel S Li, and Andrew W Siu, and Johnny C Liyu, and Elice C Chan
Department of Optometry and Radiography, Hong Kong Polytechnic University Kowloon, Hong Kong SAR, China.

OBJECTIVE This study compared the effects of pupil variation on light detection and temporal modulation across the central visual field. METHODS Light detection sensitivity (LDS) and low flickering frequency (6 Hz) temporal modulation sensitivity (TMS) of 20 young subjects were measured from the central visual field of the right eyes using an autumated perimeter (Medmont M600). The measurements were taken under 3 artificial pupils, i.e. 3 mm, 4.3 mm and 6 mm diameters. The sensitivities were grouped and averaged for different retinal eccentricities (3 degrees, 6 degrees, 10 degrees, and 15 degrees). RESULTS TMS and LDS were reduced with increasing retinal eccentricities (P < 0.001) and decreasing pupil diameters (P < 0.001). TMS collected from all pupil diameters were significantly different from each other (P < 0.001). Similarly, LDS under 3 mm pupil was statistically different from those of 4.3 mm and 6 mm (P < 0.003). Comparison of the hills of vision showed that pupil variation resulted in significantly different slopes (P = 0.001). The slopes were also found to be significantly different between TMS and LDS (P = 0.012). CONCLUSIONS The data showed that dilated pupil resulted in significantly higher sensitivities than those of smaller pupil for both visual functions. The difference in the slopes of hills of vision also suggested that the variation in retinal illumination affected the visual responses differently at various retinal eccentricities for TMS and LDS.

UI MeSH Term Description Entries
D008027 Light That portion of the electromagnetic spectrum in the visible, ultraviolet, and infrared range. Light, Visible,Photoradiation,Radiation, Visible,Visible Radiation,Photoradiations,Radiations, Visible,Visible Light,Visible Radiations
D008297 Male Males
D010775 Photic Stimulation Investigative technique commonly used during ELECTROENCEPHALOGRAPHY in which a series of bright light flashes or visual patterns are used to elicit brain activity. Stimulation, Photic,Visual Stimulation,Photic Stimulations,Stimulation, Visual,Stimulations, Photic,Stimulations, Visual,Visual Stimulations
D011680 Pupil The aperture in the iris through which light passes. Pupils
D012025 Reflex, Pupillary Constriction of the pupil in response to light stimulation of the retina. It refers also to any reflex involving the iris, with resultant alteration of the diameter of the pupil. (Cline et al., Dictionary of Visual Science, 4th ed) Pupillary Reflex
D012160 Retina The ten-layered nervous tissue membrane of the eye. It is continuous with the OPTIC NERVE and receives images of external objects and transmits visual impulses to the brain. Its outer surface is in contact with the CHOROID and the inner surface with the VITREOUS BODY. The outer-most layer is pigmented, whereas the inner nine layers are transparent. Ora Serrata
D005260 Female Females
D005425 Flicker Fusion The point or frequency at which all flicker of an intermittent light stimulus disappears. Flicker Fusions,Fusion, Flicker,Fusions, Flicker
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D014785 Vision, Ocular The process in which light signals are transformed by the PHOTORECEPTOR CELLS into electrical signals which can then be transmitted to the brain. Vision,Light Signal Transduction, Visual,Ocular Vision,Visual Light Signal Transduction,Visual Phototransduction,Visual Transduction,Phototransduction, Visual,Transduction, Visual

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