Biomaterial Database

Occupational allergy from 1,2-benzisothiazolin-3-one and other preservatives in plastic emulsions. 1976

N B Pedersen

Two male employees in an industry producing plastic emulsions acquired contact dermatitis from preservatives. One was sensitized to both components in a preservative, i.e. 1,2-benzisothiazolin-3-one and ethylene diamine. The other man acquired a contact allergy to 1,2-benzisothiazolin-3-one and to another preservative, formaldehyde.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D009783	Dermatitis, Occupational	A recurrent contact dermatitis caused by substances found in the work place.	Occupational Dermatitis,Dermatosis, Industrial,Industrial Dermatosis,Dermatitides, Occupational,Dermatoses, Industrial,Industrial Dermatoses,Occupational Dermatitides
D009787	Occupational Medicine	Medical specialty concerned with the promotion and maintenance of the physical and mental health of employees in occupational settings.	Industrial Medicine,Medicine, Industrial,Medicine, Occupational
D010328	Patch Tests	Skin tests in which the sensitizer is applied to a patch of cotton cloth or gauze held in place for approximately 48-72 hours. It is used for the elicitation of a contact hypersensitivity reaction.	Patch Testing,Patch Test,Patch Testings,Test, Patch,Testing, Patch,Testings, Patch,Tests, Patch
D010969	Plastics	Polymeric materials (usually organic) of large molecular weight which can be shaped by flow. Plastic usually refers to the final product with fillers, plasticizers, pigments, and stabilizers included (versus the resin, the homogeneous polymeric starting material). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)	Plastic
D002617	Chemical Industry	The aggregate enterprise of manufacturing and technically producing chemicals. (From Random House Unabridged Dictionary, 2d ed)	Industry, Chemical,Chemical Industries,Industries, Chemical
D003877	Dermatitis, Contact	A type of acute or chronic skin reaction in which sensitivity is manifested by reactivity to materials or substances coming in contact with the skin. It may involve allergic or non-allergic mechanisms.	Contact Dermatitis,Dermatitis Venenata,Eczema, Contact,Hypersensitivity, Contact,Sensitivity, Contact,Contact Dermatitides,Contact Eczema,Contact Hypersensitivities,Contact Hypersensitivity,Contact Sensitivities,Contact Sensitivity,Dermatitides, Contact,Hypersensitivities, Contact,Sensitivities, Contact
D005029	Ethylenediamines	Derivatives of ethylenediamine (the structural formula NH2CH2CH2NH2).
D005557	Formaldehyde	A highly reactive aldehyde gas formed by oxidation or incomplete combustion of hydrocarbons. In solution, it has a wide range of uses: in the manufacture of resins and textiles, as a disinfectant, and as a laboratory fixative or preservative. Formaldehyde solution (formalin) is considered a hazardous compound, and its vapor toxic. (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p717)	Formalin,Formol,Methanal,Oxomethane