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We examined the effects of a xanthine derivative, propentofylline, on recovery of brain function following TCI in 23 adult mongrel dogs. TCI was produced by clamping ascending aorta with aortoatrial bypass formation. The dogs were divided into 3 groups: preischemic administration (0.3 mg.kg-1.min-1, 30 min), post-ischemic administration (0.5 mg.kg-1.min-1, 6h) and control. The progress of recovery of EEG, respiration, reflexes, motor functions, arousal state and behavior were observed for 7 days after TCI and the latter 5 functions were analysed using neurologic deficit score (NDS). Propentofylline shortened the time necessary for reappearance of EEG after the starting of recirculation but could not improve the NDS.
F Kadoya, and
F Hayashi, and
T Senda, and
Y Yoshimura, and
H Imon, and
T Arai
November 1987,
Masui. The Japanese journal of anesthesiology,
F Kadoya, and
F Hayashi, and
T Senda, and
Y Yoshimura, and
H Imon, and
T Arai
January 1993,
Acta neurochirurgica. Supplementum,
F Kadoya, and
F Hayashi, and
T Senda, and
Y Yoshimura, and
H Imon, and
T Arai
September 1987,
Brain research,
F Kadoya, and
F Hayashi, and
T Senda, and
Y Yoshimura, and
H Imon, and
T Arai
October 1994,
General pharmacology,
F Kadoya, and
F Hayashi, and
T Senda, and
Y Yoshimura, and
H Imon, and
T Arai
January 1983,
Circulatory shock,
F Kadoya, and
F Hayashi, and
T Senda, and
Y Yoshimura, and
H Imon, and
T Arai
July 1994,
Stroke,
F Kadoya, and
F Hayashi, and
T Senda, and
Y Yoshimura, and
H Imon, and
T Arai
May 1991,
Stroke,
F Kadoya, and
F Hayashi, and
T Senda, and
Y Yoshimura, and
H Imon, and
T Arai
January 1993,
In vivo (Athens, Greece),
F Kadoya, and
F Hayashi, and
T Senda, and
Y Yoshimura, and
H Imon, and
T Arai
January 2001,
Journal of the neurological sciences,
F Kadoya, and
F Hayashi, and
T Senda, and
Y Yoshimura, and
H Imon, and
T Arai
February 1994,
Critical care medicine,
