BIOMAT Database Logo BIOMAT Database Logo

Uridine excess does not interfere with the antiretroviral efficacy of nucleoside analogue reverse transcriptase inhibitors. 2003

Eva C Koch, and Josef Schneider, and Roland Weis, and Björn Penning, and Ulrich A Walker

UI MeSH Term Description Entries
D007963 Leukocytes, Mononuclear Mature LYMPHOCYTES and MONOCYTES transported by the blood to the body's extravascular space. They are morphologically distinguishable from mature granulocytic leukocytes by their large, non-lobed nuclei and lack of coarse, heavily stained cytoplasmic granules. Mononuclear Leukocyte,Mononuclear Leukocytes,PBMC Peripheral Blood Mononuclear Cells,Peripheral Blood Human Mononuclear Cells,Peripheral Blood Mononuclear Cell,Peripheral Blood Mononuclear Cells,Leukocyte, Mononuclear
D002460 Cell Line Established cell cultures that have the potential to propagate indefinitely. Cell Lines,Line, Cell,Lines, Cell
D002478 Cells, Cultured Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others. Cultured Cells,Cell, Cultured,Cultured Cell
D004336 Drug Antagonism Phenomena and pharmaceutics of compounds that inhibit the function of agonists (DRUG AGONISM) and inverse agonists (DRUG INVERSE AGONISM) for a specific receptor. On their own, antagonists produce no effect by themselves to a receptor, and are said to have neither intrinsic activity nor efficacy. Antagonism, Drug,Antagonisms, Drug,Drug Antagonisms
D006367 HeLa Cells The first continuously cultured human malignant CELL LINE, derived from the cervical carcinoma of Henrietta Lacks. These cells are used for, among other things, VIRUS CULTIVATION and PRECLINICAL DRUG EVALUATION assays. Cell, HeLa,Cells, HeLa,HeLa Cell
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D014529 Uridine A ribonucleoside in which RIBOSE is linked to URACIL. Allo-Uridine,Allouridine,Allo Uridine
D015496 CD4-Positive T-Lymphocytes A critical subpopulation of T-lymphocytes involved in the induction of most immunological functions. The HIV virus has selective tropism for the T4 cell which expresses the CD4 phenotypic marker, a receptor for HIV. In fact, the key element in the profound immunosuppression seen in HIV infection is the depletion of this subset of T-lymphocytes. T4 Cells,T4 Lymphocytes,CD4-Positive Lymphocytes,CD4 Positive T Lymphocytes,CD4-Positive Lymphocyte,CD4-Positive T-Lymphocyte,Lymphocyte, CD4-Positive,Lymphocytes, CD4-Positive,T-Lymphocyte, CD4-Positive,T-Lymphocytes, CD4-Positive,T4 Cell,T4 Lymphocyte
D015497 HIV-1 The type species of LENTIVIRUS and the etiologic agent of AIDS. It is characterized by its cytopathic effect and affinity for the T4-lymphocyte. Human immunodeficiency virus 1,HIV-I,Human Immunodeficiency Virus Type 1,Immunodeficiency Virus Type 1, Human
D015658 HIV Infections Includes the spectrum of human immunodeficiency virus infections that range from asymptomatic seropositivity, thru AIDS-related complex (ARC), to acquired immunodeficiency syndrome (AIDS). HTLV-III Infections,HTLV-III-LAV Infections,T-Lymphotropic Virus Type III Infections, Human,HIV Coinfection,Coinfection, HIV,Coinfections, HIV,HIV Coinfections,HIV Infection,HTLV III Infections,HTLV III LAV Infections,HTLV-III Infection,HTLV-III-LAV Infection,Infection, HIV,Infection, HTLV-III,Infection, HTLV-III-LAV,Infections, HIV,Infections, HTLV-III,Infections, HTLV-III-LAV,T Lymphotropic Virus Type III Infections, Human

Related Publications

Eva C Koch, and Josef Schneider, and Roland Weis, and Björn Penning, and Ulrich A Walker
Toxicity of nucleoside-analogue reverse-transcriptase inhibitors.
March 2000, Lancet (London, England),
Eva C Koch, and Josef Schneider, and Roland Weis, and Björn Penning, and Ulrich A Walker
Nucleoside and nucleotide analogue reverse transcriptase inhibitors: a clinical review of antiretroviral resistance.
December 2003, Antiviral therapy,
Eva C Koch, and Josef Schneider, and Roland Weis, and Björn Penning, and Ulrich A Walker
Toxicity of non-nucleoside analogue reverse transcriptase inhibitors.
May 2003, Seminars in liver disease,
Eva C Koch, and Josef Schneider, and Roland Weis, and Björn Penning, and Ulrich A Walker
Clinical efficacy of antiretroviral combination therapy based on protease inhibitors or non-nucleoside analogue reverse transcriptase inhibitors: indirect comparison of controlled trials.
January 2004, BMJ (Clinical research ed.),
Eva C Koch, and Josef Schneider, and Roland Weis, and Björn Penning, and Ulrich A Walker
Mitochondrial toxicity of nucleoside analogue reverse transcriptase inhibitors: a looming obstacle for long-term antiretroviral therapy?
February 2000, Current opinion in infectious diseases,
Eva C Koch, and Josef Schneider, and Roland Weis, and Björn Penning, and Ulrich A Walker
Mitochondrial toxicities of nucleoside analogue reverse transcriptase inhibitors in AIDS cases.
January 2014, Indian journal of sexually transmitted diseases and AIDS,
Eva C Koch, and Josef Schneider, and Roland Weis, and Björn Penning, and Ulrich A Walker
Nucleoside analogue reverse transcriptase inhibitors differentially inhibit human LINE-1 retrotransposition.
February 2008, PloS one,
Eva C Koch, and Josef Schneider, and Roland Weis, and Björn Penning, and Ulrich A Walker
Discontinuation of non-nucleoside reverse transcriptase inhibitor-based highly active antiretroviral therapy due to nucleoside analogue reverse transcriptase inhibitor-related metabolic toxicity.
May 2007, International journal of STD & AIDS,
Eva C Koch, and Josef Schneider, and Roland Weis, and Björn Penning, and Ulrich A Walker
The emerging roles of non-nucleoside reverse transcriptase inhibitors in antiretroviral therapy.
January 2001, Drugs,
Eva C Koch, and Josef Schneider, and Roland Weis, and Björn Penning, and Ulrich A Walker
[Non-nucleoside reverse transcriptase inhibitors].
June 2000, Annales de medecine interne,
Copied contents to your clipboard!