-transparent.png){kind=logo}
Polycystic liver disease is characterized by the presence of multiple bile duct-derived epithelial cysts scattered in the liver parenchyma. The natural history and clinical manifestations of polycystic liver disease are based on the disease as it manifests in patients with autosomal dominant polycystic kidney disease (ADPKD). The occurrence of polycystic liver disease independently from polycystic kidney disease has been known for a long time. More recently, a gene for autosomal dominant polycystic liver disease has been identified on chromosome 19p 13.2-13.1. Isolated polycystic liver disease is underdiagnosed and genetically distinct from polycystic liver disease associated with ADPKD but with similar pathogenesis and clinical manifestations. We report here two men with polycystic liver disease no associated with ADPKD. Ultrasound and computed tomography imaging were effective in documenting the underlying lesions non-invasively.
R Peces, and
P González, and
J L Venegas
July 2012,
Pediatric nephrology (Berlin, Germany),
R Peces, and
P González, and
J L Venegas
May 2019,
The New England journal of medicine,
R Peces, and
P González, and
J L Venegas
January 1996,
Urologia internationalis,
R Peces, and
P González, and
J L Venegas
September 2014,
American family physician,
R Peces, and
P González, and
J L Venegas
July 1992,
Deutsche medizinische Wochenschrift (1946),
R Peces, and
P González, and
J L Venegas
March 2010,
Advances in chronic kidney disease,
R Peces, and
P González, and
J L Venegas
March 2019,
Lancet (London, England),
R Peces, and
P González, and
J L Venegas
May 1994,
BMJ (Clinical research ed.),
R Peces, and
P González, and
J L Venegas
January 2006,
Duodecim; laaketieteellinen aikakauskirja,
R Peces, and
P González, and
J L Venegas
January 2003,
Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia,
