BIOMAT Database Logo BIOMAT Database Logo

[A successful treatment with micafungin of candidemia due to Candida krusei]. 2003

Masato Nonoyama, and Hikaru Kume, and Ken Kumagai, and Kazui Souma, and Keisuke Sunakawa
Department of Infectious Diseases, Kitasato University School of Medicine.

We report a case of candidemia due to Candida krusei after subarachinoid hemorrhage. A 51 year-old male patient consulted us for high fever and increase of CRP 10 days post operation against subarachinoid hemorrhage. There was a temporary decrease in the CRP after administration of ceftazidime (CAZ) but it again when treatment with CAZ was stopped. Because of detected Candida sp. by blood culture, fluconazole was administered i.v. for 5 days, but C. krusei was positive during the treatment. Therefore, fluconazole was replaced with micafungin. The patient became better after the administration with micafungin for 14 days without side effect. Micafungin is effective against candidemia due to C. krusei.

UI MeSH Term Description Entries
D008074 Lipoproteins Lipid-protein complexes involved in the transportation and metabolism of lipids in the body. They are spherical particles consisting of a hydrophobic core of TRIGLYCERIDES and CHOLESTEROL ESTERS surrounded by a layer of hydrophilic free CHOLESTEROL; PHOSPHOLIPIDS; and APOLIPOPROTEINS. Lipoproteins are classified by their varying buoyant density and sizes. Circulating Lipoproteins,Lipoprotein,Lipoproteins, Circulating
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D010456 Peptides, Cyclic Peptides whose amino acid residues are linked together forming a circular chain. Some of them are ANTI-INFECTIVE AGENTS; some are biosynthesized non-ribosomally (PEPTIDE BIOSYNTHESIS, NON-RIBOSOMAL). Circular Peptide,Cyclic Peptide,Cyclic Peptides,Cyclopeptide,Orbitide,Circular Peptides,Cyclopeptides,Orbitides,Peptide, Circular,Peptide, Cyclic,Peptides, Circular
D002177 Candidiasis Infection with a fungus of the genus CANDIDA. It is usually a superficial infection of the moist areas of the body and is generally caused by CANDIDA ALBICANS. (Dorland, 27th ed) Candida Infection,Moniliasis,Candida Infections,Candidiases,Infection, Candida,Moniliases
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000077551 Micafungin A cyclic lipo-hexapeptide echinocandin antifungal agent that is used for the treatment and prevention of CANDIDIASIS. FK 463,FK-463,FK463,Micafungin Sodium,Mycamine
D000935 Antifungal Agents Substances that destroy fungi by suppressing their ability to grow or reproduce. They differ from FUNGICIDES, INDUSTRIAL because they defend against fungi present in human or animal tissues. Anti-Fungal Agents,Antifungal Agent,Fungicides, Therapeutic,Antibiotics, Antifungal,Therapeutic Fungicides,Agent, Antifungal,Anti Fungal Agents,Antifungal Antibiotics
D016469 Fungemia The presence of fungi circulating in the blood. Opportunistic fungal sepsis is seen most often in immunosuppressed patients with severe neutropenia or in postoperative patients with intravenous catheters and usually follows prolonged antibiotic therapy.
D054714 Echinocandins Cyclic hexapeptides of proline-ornithine-threonine-proline-threonine-serine. The cyclization with a single non-peptide bond can lead them to be incorrectly called DEPSIPEPTIDES, but the echinocandins lack ester links. Antifungal activity is via inhibition of 1,3-beta-glucan synthase production of BETA-GLUCANS. Aculeacin,Echinocandin,Pneumocandin,Aculeacins,Mulundocandins,Pneumocandins

Related Publications

Masato Nonoyama, and Hikaru Kume, and Ken Kumagai, and Kazui Souma, and Keisuke Sunakawa
Outcomes with micafungin in patients with candidaemia or invasive candidiasis due to Candida glabrata and Candida krusei.
February 2011, The Journal of antimicrobial chemotherapy,
Masato Nonoyama, and Hikaru Kume, and Ken Kumagai, and Kazui Souma, and Keisuke Sunakawa
Successful treatment with caspofungin of refractory Candida krusei candidemia in a very low birth weight preterm infant.
May 2009, The Pediatric infectious disease journal,
Masato Nonoyama, and Hikaru Kume, and Ken Kumagai, and Kazui Souma, and Keisuke Sunakawa
[Successful treatment with micafungin in a case of candidemia associated with pneumonia].
April 2005, Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases,
Masato Nonoyama, and Hikaru Kume, and Ken Kumagai, and Kazui Souma, and Keisuke Sunakawa
Breakthrough candidemia due to multidrug-resistant Candida glabrata during prophylaxis with a low dose of micafungin.
January 2014, Antimicrobial agents and chemotherapy,
Masato Nonoyama, and Hikaru Kume, and Ken Kumagai, and Kazui Souma, and Keisuke Sunakawa
Pneumonia due to Candida krusei.
December 2002, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases,
Masato Nonoyama, and Hikaru Kume, and Ken Kumagai, and Kazui Souma, and Keisuke Sunakawa
Successful treatment of recurrent candidemia due to candidal thrombophlebitis associated with a central venous catheter using a combination of fosfluconazole and micafungin.
January 2013, Internal medicine (Tokyo, Japan),
Masato Nonoyama, and Hikaru Kume, and Ken Kumagai, and Kazui Souma, and Keisuke Sunakawa
Pediatric Risk Factors for Candidemia Secondary to Candida glabrata and Candida krusei Species.
September 2013, Journal of the Pediatric Infectious Diseases Society,
Masato Nonoyama, and Hikaru Kume, and Ken Kumagai, and Kazui Souma, and Keisuke Sunakawa
A case of fungemia due to Candida krusei.
January 1999, Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology,
Masato Nonoyama, and Hikaru Kume, and Ken Kumagai, and Kazui Souma, and Keisuke Sunakawa
Successful treatment of Candida krusei fungemia with amphotericin B and caspofungin.
November 2006, Medical mycology,
Masato Nonoyama, and Hikaru Kume, and Ken Kumagai, and Kazui Souma, and Keisuke Sunakawa
Successful treatment of Candida tropicalis osteomyelitis with Micafungin in a leukemia patient.
January 2016, IDCases,
Copied contents to your clipboard!