Biomaterial Database

Local specific immunity in infants with spastic bronchitis and bronchopneumonia. 1977

V Kikindjanin

In 27 infants with spastic bronchitis and in 23 infants with bronchopneumonia the values of IgA, IgG and IgM in bronchial secretion were determined by single radial immunodiffusion method. In both group A and B the frequencies of IgA and IgG were statistical significant. The IgM frequency was significant only in group A. The mean values of IgA and IgG were considerably higher in relation to mean IgM values. The presence of IgA and IgG was found in the first bronchial secretion sample in all investigated infants. The presence of IgM in bronchial secretion was found in high percentage. However, the presence of IgM was found in ten investigated infants only in second bronchial secretion sample. It was concluded that for estimation of real state of specific local immunity on bronchial mucosa it is necessary to determine the immunglobulin values twice and that at three days interval. In this study the local immunoglobulin deficiency was found in none case.

UI	MeSH Term	Description	Entries
D007070	Immunoglobulin A	Represents 15-20% of the human serum immunoglobulins, mostly as the 4-chain polymer in humans or dimer in other mammals. Secretory IgA (IMMUNOGLOBULIN A, SECRETORY) is the main immunoglobulin in secretions.	IgA,IgA Antibody,IgA1,IgA2,Antibody, IgA
D007074	Immunoglobulin G	The major immunoglobulin isotype class in normal human serum. There are several isotype subclasses of IgG, for example, IgG1, IgG2A, and IgG2B.	Gamma Globulin, 7S,IgG,IgG Antibody,Allerglobuline,IgG(T),IgG1,IgG2,IgG2A,IgG2B,IgG3,IgG4,Immunoglobulin GT,Polyglobin,7S Gamma Globulin,Antibody, IgG,GT, Immunoglobulin
D007075	Immunoglobulin M	A class of immunoglobulin bearing mu chains (IMMUNOGLOBULIN MU-CHAINS). IgM can fix COMPLEMENT. The name comes from its high molecular weight and originally was called a macroglobulin.	Gamma Globulin, 19S,IgM,IgM Antibody,IgM1,IgM2,19S Gamma Globulin,Antibody, IgM
D007223	Infant	A child between 1 and 23 months of age.	Infants
D001991	Bronchitis	Inflammation of the large airways in the lung including any part of the BRONCHI, from the PRIMARY BRONCHI to the TERTIARY BRONCHI.	Bronchitides
D001996	Bronchopneumonia	Inflammation of the lung parenchyma that is associated with BRONCHITIS, usually involving lobular areas from TERMINAL BRONCHIOLES to the PULMONARY ALVEOLI. The affected areas become filled with exudate that forms consolidated patches.	Bronchial Pneumonia,Bronchial Pneumonias,Bronchopneumonias,Pneumonia, Bronchial,Pneumonias, Bronchial
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D013183	Sputum	Material coughed up from the lungs and expectorated via the mouth. It contains MUCUS, cellular debris, and microorganisms. It may also contain blood or pus.	Sputum, Induced,Induced Sputum,Induced Sputums,Sputums,Sputums, Induced