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In our series of 33 children who underwent temporal and extended temporal lobe resections because of seizures, the average age at surgery was 7 years, 11 months. Sixteen cases (48%) were diagnosed as having tumors: low-grade astrocytoma (6), hamartoma (5), and ganglioglioma/neuroma (5). Other pathologic diagnoses included one or more cytoarchitectural abnormalities and/or reactive changes. Due to a more aggressive and early radiologic and electrophysiologic investigation of children with seizures, a resectable focus, e.g. neoplasm or structural abnormality, was found in a much younger age group of patients than previously reported. In children who had intractable seizures but normal radiologic studies, positron emission tomography was of great value in localizing the seizure focus. In a group of children with infantile spasms, seizures were controlled following the identification and resection of a focal lesion. Prompt detection and precise localization of lesions in the temporal lobe in the pediatric population may lead to surgical management and seizure control.
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H T Chugani, and
Y G Comair, and
H V Vinters, and
W D Shields, and
D A Shewmon
January 1991,
Developmental medicine and child neurology,
P D Adelson, and
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H T Chugani, and
Y G Comair, and
H V Vinters, and
W D Shields, and
D A Shewmon
November 1993,
Neurology,
P D Adelson, and
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Y G Comair, and
H V Vinters, and
W D Shields, and
D A Shewmon
July 1995,
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P D Adelson, and
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Y G Comair, and
H V Vinters, and
W D Shields, and
D A Shewmon
March 1992,
Brain & development,
P D Adelson, and
W J Peacock, and
H T Chugani, and
Y G Comair, and
H V Vinters, and
W D Shields, and
D A Shewmon
February 1991,
Pediatrics,
P D Adelson, and
W J Peacock, and
H T Chugani, and
Y G Comair, and
H V Vinters, and
W D Shields, and
D A Shewmon
January 1990,
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P D Adelson, and
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H T Chugani, and
Y G Comair, and
H V Vinters, and
W D Shields, and
D A Shewmon
January 2010,
Journal of neurosurgery,
P D Adelson, and
W J Peacock, and
H T Chugani, and
Y G Comair, and
H V Vinters, and
W D Shields, and
D A Shewmon
January 1992,
Acta neuropathologica,
P D Adelson, and
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H T Chugani, and
Y G Comair, and
H V Vinters, and
W D Shields, and
D A Shewmon
July 1991,
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P D Adelson, and
W J Peacock, and
H T Chugani, and
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H V Vinters, and
W D Shields, and
D A Shewmon
November 1980,
Annals of neurology,
