Biomaterial Database

Anthrax and the etiology of the English sweating sickness. 2004

Edward McSweegan

edward@mcsweegan.com

In 2001, spores of Bacillus anthracis were deliberately sent through the United States postal system, resulting in five deaths from inhalational anthrax. Rarely observed clinical symptoms associated with these cases led to a hypothesis about the etiology of the English Sweating Sickness. The disease appeared sporadically in England between 1485 and 1551. Numerous viruses have been proposed as possible causes of the "English Sweat". Anthrax has not previously been considered because, documented cases of inhalational anthrax have been rare and pronounced sweating was not a noted symptom of the more common cutaneous and gastrointestinal forms of anthrax. Victims of the English Sweating Sickness have recently been identified in undisturbed tombs. It may be possible to examine those bodies and coffins for the presence of resilient anthrax spores and DNA using modern genomic tools.

UI	MeSH Term	Description	Entries
D002102	Cadaver	A dead body, usually a human body.	Corpse,Cadavers,Corpses
D004739	England	A part of Great Britain within the United Kingdom.
D005554	Forensic Medicine	The application of medical knowledge to questions of law.	Legal Medicine,Medicine, Forensic,Medicine, Legal
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000881	Anthrax	An acute infection caused by the spore-forming bacteria BACILLUS ANTHRACIS. It commonly affects hoofed animals such as sheep and goats. Infection in humans often involves the skin (cutaneous anthrax), the lungs (inhalation anthrax), or the gastrointestinal tract. Anthrax is not contagious and can be treated with antibiotics.	Bacillus anthracis Infection,Bacillus anthracis Infections
D049668	History, 15th Century	Time period from 1401 through 1500 of the common era.	15th Century History,15th Cent. History (Medicine),15th Cent. History of Medicine,15th Cent. Medicine,Historical Events, 15th Century,History of Medicine, 15th Cent.,History, Fifteenth Century,Medical History, 15th Cent.,Medicine, 15th Cent.,15th Cent. Histories (Medicine),15th Century Histories,Cent. Histories, 15th (Medicine),Cent. History, 15th (Medicine),Century Histories, 15th,Century Histories, Fifteenth,Century History, 15th,Century History, Fifteenth,Fifteenth Century Histories,Fifteenth Century History,Histories, 15th Cent. (Medicine),Histories, 15th Century,Histories, Fifteenth Century,History, 15th Cent. (Medicine)
D049669	History, 16th Century	Time period from 1501 through 1600 of the common era.	16th Century History,16th Cent. History (Medicine),16th Cent. History of Medicine,16th Cent. Medicine,Historical Events, 16th Century,History of Medicine, 16th Cent.,History, Sixteenth Century,Medical History, 16th Cent.,Medicine, 16th Cent.,16th Cent. Histories (Medicine),16th Century Histories,Cent. Histories, 16th (Medicine),Cent. History, 16th (Medicine),Century Histories, 16th,Century Histories, Sixteenth,Century History, 16th,Century History, Sixteenth,Histories, 16th Cent. (Medicine),Histories, 16th Century,Histories, Sixteenth Century,History, 16th Cent. (Medicine),Sixteenth Century Histories,Sixteenth Century History
D018614	Sweating Sickness	A clinical condition characterized by fever and profuse sweating and associated with high mortality. It occurred in epidemic form five times in the fifteenth and sixteenth centuries in England, first in 1485 and last in 1551, specially during the summer and early autumn, attacking the relatively affluent adult male population. The etiology was unknown.	English Sweating Sickness,Sudor Anglicus,Sickness, Sweating