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The effects of sedation by intravenous fentanyl on the rate-pressure product (pulse rate x systolic blood pressure/100), arterial oxygen saturation, electrocardiographic change, and serum cortisol concentration were studied during gastroduodenoscopy in 84 patients randomized to receive fentanyl or no intravenous sedative (controls). Fentanyl administration increased the tolerance of patients and attenuated the endoscopy-induced rise in rate-pressure product and serum cortisol concentration. Desaturation of arterial oxygen was minimal and there was no difference in arterial oxygen saturation between the fentanyl group and the control group. Therefore, fentanyl appears to be a favorable sedative for upper gastrointestinal endoscopy, since its administration increased the tolerance of patients and decreased cardiac oxygen consumption.
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Y Kinoshita, and
N Kitajima, and
T Itoh, and
K Nishiyama, and
M Tojo, and
T Yano, and
T Inatome, and
H Fukuzaki, and
T Chiba
October 2007,
Paediatric anaesthesia,
S Ishido, and
Y Kinoshita, and
N Kitajima, and
T Itoh, and
K Nishiyama, and
M Tojo, and
T Yano, and
T Inatome, and
H Fukuzaki, and
T Chiba
July 1991,
Gut,
S Ishido, and
Y Kinoshita, and
N Kitajima, and
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M Tojo, and
T Yano, and
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H Fukuzaki, and
T Chiba
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British journal of anaesthesia,
S Ishido, and
Y Kinoshita, and
N Kitajima, and
T Itoh, and
K Nishiyama, and
M Tojo, and
T Yano, and
T Inatome, and
H Fukuzaki, and
T Chiba
June 2013,
World journal of gastroenterology,
S Ishido, and
Y Kinoshita, and
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K Nishiyama, and
M Tojo, and
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T Inatome, and
H Fukuzaki, and
T Chiba
February 2003,
Masui. The Japanese journal of anesthesiology,
S Ishido, and
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K Nishiyama, and
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T Inatome, and
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T Chiba
August 2009,
Alimentary pharmacology & therapeutics,
S Ishido, and
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N Kitajima, and
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T Chiba
January 2010,
Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association,
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T Chiba
September 2021,
Canadian journal of anaesthesia = Journal canadien d'anesthesie,
S Ishido, and
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T Chiba
January 1989,
Gastrointestinal endoscopy,
S Ishido, and
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T Chiba
March 1991,
Ugeskrift for laeger,
