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Twin-twin transfusion syndrome in a dizygotic monochorionic-diamniotic twin pregnancy. 2003
R A Quintero, and
O T Mueller, and
J M Martínez, and
J Arroyo, and
E Gilbert-Barness, and
D Hilbelink, and
P Papenhausen, and
M Sutcliffe
Florida Institute for Fetal Diagnosis and Therapy, St. Joseph's Women's Hospital, Tampa, Florida, USA.
We present a case of twin-twin transfusion syndrome with discordant gender. Monochorionicity was confirmed by surgical pathology. Cytogenetic analysis showed normal 46,XX and 46,XY karyotypes. Microsatellite analysis using reliable pericentromeric markers was consistent with dispermic fertilization of two separate ova. This suggests that monochorionicity, rather than zygosity, may be responsible for the development of placental vascular anastomoses.
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