Pulmonary artery involvement in Wegener's granulomatosis. 2003

T Clark, and G S Hoffman
Cleveland Clinic Foundation, Center for Vasculitis Care and Research, Cleveland, Ohio, USA.

Classification and nomenclature schemes are guidelines and are not intended to recognize and distinguish the entire spectrum of any single disease. It may in fact be misleading to suggest that a classic presentation of a given disease plus atypical features should be considered an "overlap" of two separate, often rare, conditions. We report a case of typical Wegener's granulomatosis (WG), with the coexistence of pulmonary artery stenosis, a lesion more commonly observed in TA. This is not the first or only example of large vessel vasculitis occurring in patients with WG. This observation cautions clinicians to avoid rigid application of classification and nomenclature systems and raises questions about determinants of vasculitis subsets and organ targeting.

UI MeSH Term Description Entries
D011651 Pulmonary Artery The short wide vessel arising from the conus arteriosus of the right ventricle and conveying unaerated blood to the lungs. Arteries, Pulmonary,Artery, Pulmonary,Pulmonary Arteries
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000792 Angiography Radiography of blood vessels after injection of a contrast medium. Arteriography,Angiogram,Angiograms,Angiographies,Arteriographies
D014890 Granulomatosis with Polyangiitis A multisystemic disease of a complex genetic background. It is characterized by inflammation of the blood vessels (VASCULITIS) leading to damage in any number of organs. The common features include granulomatous inflammation of the RESPIRATORY TRACT and KIDNEYS. Most patients have measurable autoantibodies (ANTINEUTROPHIL CYTOPLASMIC ANTIBODIES) against MYELOBLASTIN. Granulomatosis, Wegener's,Wegener Granulomatosis,Wegener's Granulomatosis,Granulomatosis with Polyangiitides,Granulomatosis, Wegener,Polyangiitides, Granulomatosis with,Polyangiitis, Granulomatosis with,with Polyangiitides, Granulomatosis,with Polyangiitis, Granulomatosis

Related Publications

T Clark, and G S Hoffman
January 1986, The Indian journal of chest diseases & allied sciences,
T Clark, and G S Hoffman
December 1984, Southern medical journal,
T Clark, and G S Hoffman
January 1973, Annals of clinical and laboratory science,
T Clark, and G S Hoffman
January 1993, Advances in experimental medicine and biology,
T Clark, and G S Hoffman
January 1982, Medicina clinica,
T Clark, and G S Hoffman
October 2008, Clinical reviews in allergy & immunology,
T Clark, and G S Hoffman
February 1995, British heart journal,
T Clark, and G S Hoffman
January 2008, Pituitary,
T Clark, and G S Hoffman
January 1967, Klinische Monatsblatter fur Augenheilkunde,
T Clark, and G S Hoffman
January 1968, Klinische Monatsblatter fur Augenheilkunde,
Copied contents to your clipboard!