Lack of enterohepatic circulation of the active metabolite of nabumetone in humans. 1992

M A Brett, and G Buscher, and E Ellrich, and W H Greb, and H J Kurth, and G Rülander, and B Schmerenbeck, and R Haddock, and A Thawley
Clinical Pharmacology Research Institute, SmithKline Beecham Pharma, Neuss, Germany.

UI MeSH Term Description Entries
D008297 Male Males
D009280 Naphthaleneacetic Acids Naphthalene derivatives containing the -CH2CCO2H radical at the 1-position, the 2-position, or both. Compounds are used as plant growth regulators to delay sprouting, exert weed control, thin fruit, etc. Acids, Naphthaleneacetic
D009994 Osmolar Concentration The concentration of osmotically active particles in solution expressed in terms of osmoles of solute per liter of solution. Osmolality is expressed in terms of osmoles of solute per kilogram of solvent. Ionic Strength,Osmolality,Osmolarity,Concentration, Osmolar,Concentrations, Osmolar,Ionic Strengths,Osmolalities,Osmolar Concentrations,Osmolarities,Strength, Ionic,Strengths, Ionic
D010919 Placebos Any dummy medication or treatment. Although placebos originally were medicinal preparations having no specific pharmacological activity against a targeted condition, the concept has been extended to include treatments or procedures, especially those administered to control groups in clinical trials in order to provide baseline measurements for the experimental protocol. Sham Treatment
D002074 Butanones Derivatives of butanone, also known as methyl ethyl ketone (with structural formula CH3COC2H5).
D002792 Cholestyramine Resin A strongly basic anion exchange resin whose main constituent is polystyrene trimethylbenzylammonium Cl(-) anion. Cholestyramine,Colestyramine,Colestyramin,Cuemid,MK-135,Quantalan,Questran,Cholestyramine Resins,Cholestyramines,Colestyramines,Colestyramins,Cuemids,MK 135,MK135,Quantalans,Questrans,Resin, Cholestyramine,Resins, Cholestyramine
D004311 Double-Blind Method A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment. Double-Masked Study,Double-Blind Study,Double-Masked Method,Double Blind Method,Double Blind Study,Double Masked Method,Double Masked Study,Double-Blind Methods,Double-Blind Studies,Double-Masked Methods,Double-Masked Studies,Method, Double-Blind,Method, Double-Masked,Methods, Double-Blind,Methods, Double-Masked,Studies, Double-Blind,Studies, Double-Masked,Study, Double-Blind,Study, Double-Masked
D004764 Enterohepatic Circulation Recycling through liver by excretion in bile, reabsorption from intestines (INTESTINAL REABSORPTION) into portal circulation, passage back into liver, and re-excretion in bile. Circulation, Enterohepatic,Entero-Hepatic Circulation,Circulation, Entero-Hepatic,Circulations, Entero-Hepatic,Circulations, Enterohepatic,Entero Hepatic Circulation,Entero-Hepatic Circulations,Enterohepatic Circulations
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000077430 Nabumetone A butanone non-steroidal anti-inflammatory drug and cyclooxygenase-2 (COX2) inhibitor that is used in the management of pain associated with OSTEOARTHRITIS and RHEUMATOID ARTHRITIS. 4-(6-Methoxy-2-naphthyl)-2-butanone,Apo-Nabumetone,Arthraxan,BRL 14777,Gen-Nabumetone,Listran,Mebutan,Nabucox,Nabumeton,Relafen,Relif,Relifex,Rhoxal-nabumetone,ApoNabumetone,Rhoxal nabumetone

Related Publications

M A Brett, and G Buscher, and E Ellrich, and W H Greb, and H J Kurth, and G Rülander, and B Schmerenbeck, and R Haddock, and A Thawley
December 1988, Fortschritte der Medizin,
M A Brett, and G Buscher, and E Ellrich, and W H Greb, and H J Kurth, and G Rülander, and B Schmerenbeck, and R Haddock, and A Thawley
November 1956, Clinical science,
M A Brett, and G Buscher, and E Ellrich, and W H Greb, and H J Kurth, and G Rülander, and B Schmerenbeck, and R Haddock, and A Thawley
January 1994, Drug metabolism and disposition: the biological fate of chemicals,
M A Brett, and G Buscher, and E Ellrich, and W H Greb, and H J Kurth, and G Rülander, and B Schmerenbeck, and R Haddock, and A Thawley
March 1993, Journal of pharmaceutical sciences,
M A Brett, and G Buscher, and E Ellrich, and W H Greb, and H J Kurth, and G Rülander, and B Schmerenbeck, and R Haddock, and A Thawley
June 1995, Clinical pharmacology and therapeutics,
M A Brett, and G Buscher, and E Ellrich, and W H Greb, and H J Kurth, and G Rülander, and B Schmerenbeck, and R Haddock, and A Thawley
January 1978, Scandinavian journal of gastroenterology,
M A Brett, and G Buscher, and E Ellrich, and W H Greb, and H J Kurth, and G Rülander, and B Schmerenbeck, and R Haddock, and A Thawley
July 2021, American journal of physiology. Gastrointestinal and liver physiology,
M A Brett, and G Buscher, and E Ellrich, and W H Greb, and H J Kurth, and G Rülander, and B Schmerenbeck, and R Haddock, and A Thawley
January 1972, Gastroenterology,
M A Brett, and G Buscher, and E Ellrich, and W H Greb, and H J Kurth, and G Rülander, and B Schmerenbeck, and R Haddock, and A Thawley
November 1991, Gastroenterology,
M A Brett, and G Buscher, and E Ellrich, and W H Greb, and H J Kurth, and G Rülander, and B Schmerenbeck, and R Haddock, and A Thawley
January 1971, The New England journal of medicine,
Copied contents to your clipboard!