-transparent.png){kind=logo}
The methylating agent streptozotocin is active in the mouse bone marrow micronucleus assay following a single intraperitoneal injection of 150-180 mg/kg. This correlates with its previously reported toxicity to mouse germ cells when administered by the same route of exposure. The potent mutagenicity of streptozotocin to strain G46 of Salmonella typhimurium is compared with its much weaker activity in strain TA1535. The genotoxicity of streptozotocin in vivo is reviewed.
Related Publications
U Liegibel, and
H Tinwell, and
R D Callander, and
P Schmezer, and
J Ashby
January 1988,
Environmental and molecular mutagenesis,
U Liegibel, and
H Tinwell, and
R D Callander, and
P Schmezer, and
J Ashby
November 2002,
Mutation research,
U Liegibel, and
H Tinwell, and
R D Callander, and
P Schmezer, and
J Ashby
February 1994,
Mutation research,
U Liegibel, and
H Tinwell, and
R D Callander, and
P Schmezer, and
J Ashby
November 1995,
Mutagenesis,
U Liegibel, and
H Tinwell, and
R D Callander, and
P Schmezer, and
J Ashby
October 1996,
Mutation research,
U Liegibel, and
H Tinwell, and
R D Callander, and
P Schmezer, and
J Ashby
November 1993,
Mutagenesis,
U Liegibel, and
H Tinwell, and
R D Callander, and
P Schmezer, and
J Ashby
September 1992,
Biological trace element research,
U Liegibel, and
H Tinwell, and
R D Callander, and
P Schmezer, and
J Ashby
January 1994,
Environmental and molecular mutagenesis,
U Liegibel, and
H Tinwell, and
R D Callander, and
P Schmezer, and
J Ashby
July 1993,
Mutagenesis,
U Liegibel, and
H Tinwell, and
R D Callander, and
P Schmezer, and
J Ashby
October 2008,
Molecular nutrition & food research,
