-transparent.png){kind=logo}
The usefulness of placental alkaline phosphatase (PLAP) as a diagnostic marker of malignancy was assessed in pleural fluid from 60 patients with effusions. Pleural fluid PLAP activities were measured by an enzyme linked immunoassay (ELISA) using the two monoclonal antibodies H17E2 and H317. Similar values were found in groups of patients with primary bronchial tumours (n = 12), secondary malignancies (n = 23), and "benign" conditions (n = 25). The highest values were found in a small subgroup of patients with metastatic ovarian carcinoma. However, the production of this enzyme by normal lung makes the measurement of PLAP in pleural fluid unhelpful as a diagnostic aid to distinguish "benign" from malignant effusions.
R J Fergusson, and
J Fisken, and
M A McIntyre, and
J E Roulston, and
R C Leonard
May 1985,
The Histochemical journal,
R J Fergusson, and
J Fisken, and
M A McIntyre, and
J E Roulston, and
R C Leonard
January 2003,
The Indian journal of chest diseases & allied sciences,
R J Fergusson, and
J Fisken, and
M A McIntyre, and
J E Roulston, and
R C Leonard
February 1985,
Cancer research,
R J Fergusson, and
J Fisken, and
M A McIntyre, and
J E Roulston, and
R C Leonard
June 1978,
Clinica chimica acta; international journal of clinical chemistry,
R J Fergusson, and
J Fisken, and
M A McIntyre, and
J E Roulston, and
R C Leonard
August 1997,
Chest,
R J Fergusson, and
J Fisken, and
M A McIntyre, and
J E Roulston, and
R C Leonard
January 1998,
Annals of clinical biochemistry,
R J Fergusson, and
J Fisken, and
M A McIntyre, and
J E Roulston, and
R C Leonard
February 2013,
Thoracic surgery clinics,
R J Fergusson, and
J Fisken, and
M A McIntyre, and
J E Roulston, and
R C Leonard
January 1989,
Surgery annual,
R J Fergusson, and
J Fisken, and
M A McIntyre, and
J E Roulston, and
R C Leonard
May 1975,
Wiener klinische Wochenschrift,
R J Fergusson, and
J Fisken, and
M A McIntyre, and
J E Roulston, and
R C Leonard
February 2001,
Diagnostic cytopathology,
