Biomaterial Database

Actinic cheilitis granulomatosa. 1992

Y Kuno, and S Sakakibara, and N Mizuno

Department of Dermatology, Nagoya City University Medical School, Japan.

A granulomatous lesion of the lips caused by UVB-photosensitivity is described. A 31-year-old Japanese man developed depigmented, swollen, erythematous lips with some erosions and bloody crusts which were present for 11 months. Histologic examination revealed a dense dermal infiltration composed mainly of lymphoid-histiocytic cells. Suprabasal clefts were associated with the invasion of lymphoid cells around them. Results of patch and photopatch testing were negative. The minimal erythema dose 24 h after irradiation was lower than normal, ranging from 295 to 330 nm. The lesion was reproduced by repeated irradiation with monochromatic light of 310 and 320 nm, but not by exposure to 250, 260, 270, 280, 290, 300, or 330 nm. Topical injection of glucocorticoids and application of sunscreen led to improvement. We propose the name "actinic cheilitis granulomatosa" for this case.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D008556	Melkersson-Rosenthal Syndrome	An idiopathic syndrome characterized by one or more of the following; recurrent orofacial swelling, relapsing facial paralysis, and fissured tongue (lingua plicata). The onset is usually in childhood and relapses are common. Cheilitis granulomatosa is a monosymptomatic variant of this condition. (Dermatol Clin 1996 Apr;14(2):371-9; Magalini & Magalini, Dictionary of Medical Syndromes, 4th ed, p531)	Cheilitis Granulomatosa, Facial Neuropathy, Orofacial Edema,Granulomatous Cheilitis,Cheilitis Granulomatosa,Cheilitis Granulomatosa, Orofacial Edema, Facial Neuropathy,Facial Neuropathy, Cheilitis Granulomatosa, Orofacial Edema,Facial Neuropathy, Orofacial Edema, Cheilitis Granulomatosa,Macrocheilia, Facial Palsy, Edema,Melkerson-Rosenthal Syndrome,Melkersson Syndrome,Melkersson-Rosenthal-Miescher Syndrome,Miescher-Melkersson-Rosenthal Granulomatous Cheilitis,Orofacial Edema, Cheilitis Granulomatosa, Facial Neuropathy,Orofacial Edema, Facial Neuropathy, Cheilitis Granulomatosa,Rosenthal-Melkerson Syndrome,Rosenthal-Melkersson Syndrome,Syndrome, Melkerson Rosenthal,Cheilitis, Miescher-Melkersson-Rosenthal Granulomatous,Granulomatous Cheilitis, Miescher-Melkersson-Rosenthal,Melkerson Rosenthal Syndrome,Melkersson Rosenthal Miescher Syndrome,Melkersson Rosenthal Syndrome,Miescher Melkersson Rosenthal Granulomatous Cheilitis,Rosenthal Melkerson Syndrome,Rosenthal Melkersson Syndrome
D010787	Photosensitivity Disorders	Abnormal responses to sunlight or artificial light due to extreme reactivity of light-absorbing molecules in tissues. It refers almost exclusively to skin photosensitivity, including sunburn, reactions due to repeated prolonged exposure in the absence of photosensitizing factors, and reactions requiring photosensitizing factors such as photosensitizing agents and certain diseases. With restricted reference to skin tissue, it does not include photosensitivity of the eye to light, as in photophobia or photosensitive epilepsy.	Actinic Reticuloid Syndrome,Dermatitis, Actinic,Photodermatitis,Chronic Actinic Dermatitis,Photosensitization,Actinic Dermatitides,Actinic Dermatitides, Chronic,Actinic Dermatitis,Actinic Dermatitis, Chronic,Actinic Reticuloid Syndromes,Chronic Actinic Dermatitides,Dermatitides, Actinic,Dermatitides, Chronic Actinic,Dermatitis, Chronic Actinic,Disorder, Photosensitivity,Disorders, Photosensitivity,Photodermatitides,Photosensitivity Disorder,Reticuloid Syndrome, Actinic,Reticuloid Syndromes, Actinic,Syndrome, Actinic Reticuloid,Syndromes, Actinic Reticuloid
D003937	Diagnosis, Differential	Determination of which one of two or more diseases or conditions a patient is suffering from by systematically comparing and contrasting results of diagnostic measures.	Diagnoses, Differential,Differential Diagnoses,Differential Diagnosis
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults