Biomaterial Database

Safety and efficacy of percutaneous injection of polyurethane elastomer (MPU) plugs for vas occlusion in man. 1992

Z W Chen, and Y Q Gu, and X W Liang, and Z G Wu, and E J Yin, and Li-Hong

National Research Institute for Family Planning, Beijing, China.

This report describes the safety and efficacy of the procedure for percutaneous injection of medical-grade polyurethane elastomer (MPU) to form plugs in the vas deferens. The injection of 0.16-0.22 ml MPU in 53 men resulted in occlusion and azoospermia in 85% of the men after 12 months; 96% achieved azoospermia by 2 years. The success rate of the method and the rate of sperm suppression to azoospermia depended on the shapes of the plugs; this was determined by palpation after insertion. There were few complications and the results are discussed in terms of the reversibility potential of this method.

UI	MeSH Term	Description	Entries
D007267	Injections	Introduction of substances into the body using a needle and syringe.	Injectables,Injectable,Injection
D008297	Male		Males
D011140	Polyurethanes	A group of thermoplastic or thermosetting polymers containing polyisocyanate. They are used as ELASTOMERS, as coatings, as fibers and as foams.	Polyisocyanates,Ostamer,Pellethane,Spandex,Ostamers,Pellethanes,Polyisocyanate,Polyurethane,Spandices
D005500	Follow-Up Studies	Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.	Followup Studies,Follow Up Studies,Follow-Up Study,Followup Study,Studies, Follow-Up,Studies, Followup,Study, Follow-Up,Study, Followup
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D012449	Safety	Freedom from exposure to danger and protection from the occurrence or risk of injury or loss. It suggests optimal precautions in the workplace, on the street, in the home, etc., and includes personal safety as well as the safety of property.	Safeties
D013245	Sterilization, Reproductive	Procedures to block or remove all or part of the genital tract for the purpose of rendering individuals sterile, incapable of reproduction. Surgical sterilization procedures are the most commonly used. There are also sterilization procedures involving chemical or physical means.	Reproductive Sterilization,Voluntary Sterilization,Female Sterilization,Female Sterilization, Voluntary,Male Sterilization,Male Sterilization, Voluntary,Female Sterilizations,Female Sterilizations, Voluntary,Male Sterilizations,Male Sterilizations, Voluntary,Reproductive Sterilizations,Sterilization, Female,Sterilization, Male,Sterilization, Voluntary,Sterilizations, Female,Sterilizations, Male,Sterilizations, Reproductive,Sterilizations, Voluntary,Voluntary Female Sterilization,Voluntary Female Sterilizations,Voluntary Male Sterilization,Voluntary Male Sterilizations,Voluntary Sterilizations
D014649	Vas Deferens	The excretory duct of the testes that carries SPERMATOZOA. It rises from the SCROTUM and joins the SEMINAL VESICLES to form the ejaculatory duct.	Ductus Deferens,Deferens, Ductus,Deferens, Vas
D019736	Prostheses and Implants	Artificial substitutes for body parts, and materials inserted into tissue for functional, cosmetic, or therapeutic purposes. Prostheses can be functional, as in the case of artificial arms and legs, or cosmetic, as in the case of an artificial eye. Implants, all surgically inserted or grafted into the body, tend to be used therapeutically. IMPLANTS, EXPERIMENTAL is available for those used experimentally.	Implants, Artificial,Prostheses and Implant,Prosthesis,Prosthetic Implant,Endoprostheses,Endoprosthesis,Prostheses,Prosthetic Implants,Artificial Implant,Artificial Implants,Implant and Prostheses,Implant, Artificial,Implant, Prosthetic,Implants and Prostheses,Implants, Prosthetic