Observations on the absorption, utilization, and excretion of vitamin B12.
1951
C L CONLEY, and
J R KREVANS, and
B F CHOW, and
C BARROWS, and
C A LANG
UI
MeSH Term
Description
Entries
D006397
Hematinics
Agents which improve the quality of the blood, increasing the hemoglobin level and the number of erythrocytes. They are used in the treatment of anemias.
A reduction in the number of circulating ERYTHROCYTES or in the quantity of HEMOGLOBIN.
Anemias
D000752
Anemia, Pernicious
A megaloblastic anemia occurring in children but more commonly in later life, characterized by histamine-fast achlorhydria, in which the laboratory and clinical manifestations are based on malabsorption of vitamin B 12 due to a failure of the gastric mucosa to secrete adequate and potent intrinsic factor. (Dorland, 27th ed)
A cobalt-containing coordination compound produced by intestinal micro-organisms and found also in soil and water. Higher plants do not concentrate vitamin B 12 from the soil and so are a poor source of the substance as compared with animal tissues. INTRINSIC FACTOR is important for the assimilation of vitamin B 12.