Biomaterial Database

Toxin production by Clostridium perfringens isolated from broiler chickens and capercaillies (Tetrao urogallus) with and without necrotizing enteritis. 1992

M Hofshagen, and H Stenwig

National Veterinary Institute, Oslo, Norway.

A total of 192 isolates of Clostridium perfringens were isolated from 99 broiler chickens and 93 capercaillies (Tetrao urogallus). Fifty of the isolates from broilers and 44 of the isolates from capercaillies were from birds with necrotizing enteritis, and the remainder were from birds without this disease. The isolates were tested for the production of three major toxins (alpha, beta, and epsilon) and four minor toxins (theta, gelatinase, mu, and nu). All isolates were found to be C. perfringens type A. Alpha toxin was produced in significantly larger amounts by isolates from birds with necrotizing enteritis than by isolates from birds without the disease, regardless of bird species. Isolates from broilers produced significantly more alpha toxin than did isolates from capercaillies.

UI	MeSH Term	Description	Entries
D011201	Poultry Diseases	Diseases of birds which are raised as a source of meat or eggs for human consumption and are usually found in barnyards, hatcheries, etc. The concept is differentiated from BIRD DISEASES which is for diseases of birds not considered poultry and usually found in zoos, parks, and the wild.	Disease, Poultry,Diseases, Poultry,Poultry Disease
D002645	Chickens	Common name for the species Gallus gallus, the domestic fowl, in the family Phasianidae, order GALLIFORMES. It is descended from the red jungle fowl of SOUTHEAST ASIA.	Gallus gallus,Gallus domesticus,Gallus gallus domesticus,Chicken
D003015	Clostridium Infections	Infections with bacteria of the genus CLOSTRIDIUM and closely related CLOSTRIDIOIDES species.	Clostridioides Infections,Clostridioides difficile Infection,Clostridioides perfringens Food Poisoning,Clostridioides perfringens Infections,Clostridioides sordellii Infection,Clostridium difficile Infections,Clostridium sordellii Infections,Clostridium difficile Infection,Clostridium perfringens Food Poisoning,Clostridium perfringens Infections,Clostridium sordellii Infection,Infections, Clostridium,Clostridioides Infection,Clostridioides perfringens Infection,Clostridium Infection,Clostridium perfringens Infection,Infection, Clostridioides difficile,Infection, Clostridioides sordellii,Infection, Clostridium,Infection, Clostridium difficile,Infection, Clostridium sordellii
D003016	Clostridium perfringens	The most common etiologic agent of GAS GANGRENE. It is differentiable into several distinct types based on the distribution of twelve different toxins.	Clostridium welchii
D004751	Enteritis	Inflammation of any segment of the SMALL INTESTINE.	Enteritides
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D001427	Bacterial Toxins	Toxic substances formed in or elaborated by bacteria; they are usually proteins with high molecular weight and antigenicity; some are used as antibiotics and some to skin test for the presence of or susceptibility to certain diseases.	Bacterial Toxin,Toxins, Bacterial,Toxin, Bacterial