Biomaterial Database

[Synchronized coronary venous retroperfusion: protection from ischemia in coronary angioplasty (PTCA)]. 1992

C A Nienaber, and T C Rehders, and M Abend, and C Chen

Abteilung für Kardiologie der Medizinischen Klinik und Poliklinik, Universitätskrankenhaus Eppendorf, Hamburg.

The potentially ischemia-protective effect of ECG-synchronized coronary venous retroperfusion (SRP) with arterial blood via the coronary sinus (CS) was assessed in 26 patients (56 +/- 10 years, 22 male, 4 female) in the clinical scenario of PTCA of a proximal LAD stenosis. In six additional patients the SRP procedure failed due to anatomical or technical reasons. In an intraindividual comparison at least two standardized balloon inflations for 60 seconds at 6-8 atm were performed in randomized order with and without continuous SRP at a flow rate of 200 +/- 46 ml/min. Under both conditions echocardiographic regional wall motion, ST depression in leads V1-6, hemodynamic parameters and symptoms expressed in a pain score were continuously monitored during angioplasty. This study revealed that the echocardiographic regional wall motion score in the perfusion territory of the dilated artery increased from 1.65 +/- 1.81 at baseline to 5.65 +/- 2.88 (p < 0.001) during a one minute dilatation without SRP. With SRP-support the regional wall motion at 1 minute angioplasty was significantly improved to 3.55 +/- 2.80 (p < 0.025). Moreover, the ischemic ECG-changes were markedly less pronounced, whereas the subjective perception of anginal pain was not different as a function of SRP-support. Thus, the simultaneous coronary venous retroperfusion with arterial blood has ischemia-protective potential in elective PTCA of a proximal LAD stenosis and may reduce ischemic dysfunction with prolonged balloon inflations.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D009200	Myocardial Contraction	Contractile activity of the MYOCARDIUM.	Heart Contractility,Inotropism, Cardiac,Cardiac Inotropism,Cardiac Inotropisms,Contractilities, Heart,Contractility, Heart,Contraction, Myocardial,Contractions, Myocardial,Heart Contractilities,Inotropisms, Cardiac,Myocardial Contractions
D003326	Coronary Circulation	The circulation of blood through the CORONARY VESSELS of the HEART.	Circulation, Coronary
D003331	Coronary Vessels	The veins and arteries of the HEART.	Coronary Arteries,Sinus Node Artery,Coronary Veins,Arteries, Coronary,Arteries, Sinus Node,Artery, Coronary,Artery, Sinus Node,Coronary Artery,Coronary Vein,Coronary Vessel,Sinus Node Arteries,Vein, Coronary,Veins, Coronary,Vessel, Coronary,Vessels, Coronary
D004562	Electrocardiography	Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.	12-Lead ECG,12-Lead EKG,12-Lead Electrocardiography,Cardiography,ECG,EKG,Electrocardiogram,Electrocardiograph,12 Lead ECG,12 Lead EKG,12 Lead Electrocardiography,12-Lead ECGs,12-Lead EKGs,12-Lead Electrocardiographies,Cardiographies,ECG, 12-Lead,EKG, 12-Lead,Electrocardiograms,Electrocardiographies, 12-Lead,Electrocardiographs,Electrocardiography, 12-Lead
D004867	Equipment Design	Methods and patterns of fabricating machines and related hardware.	Design, Equipment,Device Design,Medical Device Design,Design, Medical Device,Designs, Medical Device,Device Design, Medical,Device Designs, Medical,Medical Device Designs,Design, Device,Designs, Device,Designs, Equipment,Device Designs,Equipment Designs
D004868	Equipment Failure	Failure of equipment to perform to standard. The failure may be due to defects or improper use.	Defects, Equipment,Device Failure,Failure, Equipment,Malfunction, Equipment,Medical Device Failure,Misuse, Equipment,Device Failure, Medical,Device Failures, Medical,Failure, Medical Device,Failures, Medical Device,Defect, Equipment,Device Failures,Equipment Defect,Equipment Defects,Equipment Failures,Equipment Malfunction,Equipment Malfunctions,Equipment Misuse,Equipment Misuses,Failure, Device,Failures, Device,Failures, Equipment,Malfunctions, Equipment,Misuses, Equipment
D005260	Female		Females
D006328	Cardiac Catheterization	Procedures in which placement of CARDIAC CATHETERS is performed for therapeutic or diagnostic procedures.	Catheterization, Cardiac,Catheterization, Heart,Heart Catheterization,Cardiac Catheterizations,Catheterizations, Cardiac,Catheterizations, Heart,Heart Catheterizations